
Tetrahedron p. 14081 - 14088 (1998)
Update date:2022-07-30
Topics:
Danieli, Bruno
Lesma, Giordano
Martinelli, Marisa
Passarella, Daniele
Peretto, Ilaria
Silvani, Alessandra
The synthesis of 5-(indol-2'-yl)pyridin-2-ones and 5-(indol-2'-yl)pyran- 2-one by Pd-catalyzed reactions is described. The best results are obtained using 2-indolylstannanes or 2-indolylzinc halides to be coupled with 5- bromopyridin-2-ones or 5-bromopyran-2-one in the presence of Pd(PPh3)4 as catalyst. Other Pd-catalyzed reactions are discussed.
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