217460-30-5

Upstream product

• 174693-04-0 (2S,4S)-2,4-dimethyl-1-heptanol 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 217460-29-2 [(2S,4S)-2,4-Dimethyl-hept-(E)-ylidene]-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine 

Relevant academic research and scientific papers

The total synthesis of (+)-pectinatone: An iterative alkylation approach based on the SAMP-hydrazone method

The marine natural product (+)-pectinatone containing 'skip' 1,3- dimethyl stereocentres was synthesised via the iterative alkylation of propanal SAMP-hydrazone with β-branched iodides. Factors affecting the selectivity of the alkylation reaction and the in situ formation of volatile β-branched iodides are described.