21752-34-1 Usage
Uses
Used in Pharmaceutical Industry:
(S)-(-)-N-(1-PHENYLETHYL)SUCCINAMIC ACID is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the chiral properties of the final products, ensuring the desired biological activity and efficacy.
Used in Chiral Drug Production:
In the pharmaceutical industry, (S)-(-)-N-(1-PHENYLETHYL)SUCCINAMIC ACID is utilized as a key component in the production of chiral drugs, where the specific spatial arrangement of atoms is crucial for the drug's therapeutic effects and to avoid potential side effects of the mirror-image isomer.
Used in Chiral Ligand Preparation for Asymmetric Catalysis:
(S)-(-)-N-(1-PHENYLETHYL)SUCCINAMIC ACID is employed as a resolving agent in the preparation of chiral ligands for asymmetric catalysis, facilitating enantioselective reactions that produce optically active compounds with high purity.
Used in Enantiomeric Separations:
As a chiral resolving agent, (S)-(-)-N-(1-PHENYLETHYL)SUCCINAMIC ACID is used for the separation of racemic mixtures, allowing for the isolation of individual enantiomers which is essential for the development of enantiomerically pure drugs.
Used in High-Performance Liquid Chromatography (HPLC):
In analytical chemistry, (S)-(-)-N-(1-PHENYLETHYL)SUCCINAMIC ACID is used in the development of chiral stationary phases for HPLC, enabling the separation and analysis of enantiomers in a variety of samples, including pharmaceuticals, agrochemicals, and environmental pollutants.
Used in the Production of Optically Pure Compounds:
(S)-(-)-N-(1-PHENYLETHYL)SUCCINAMIC ACID is utilized in the synthesis processes aimed at producing optically pure compounds, which are essential in various chemical and pharmaceutical applications where the stereochemistry significantly influences the compound's properties and performance.
Check Digit Verification of cas no
The CAS Registry Mumber 21752-34-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,7,5 and 2 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 21752-34:
(7*2)+(6*1)+(5*7)+(4*5)+(3*2)+(2*3)+(1*4)=91
91 % 10 = 1
So 21752-34-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO3/c1-9(10-5-3-2-4-6-10)13-11(14)7-8-12(15)16/h2-6,9H,7-8H2,1H3,(H,13,14)(H,15,16)/t9-/m0/s1
21752-34-1Relevant academic research and scientific papers
A convenient one-pot synthesis of polysubstituted pyrroles from N-protected succinimides
Kobeissi, Marwan,Yazbeck, Ogaritte,Chreim, Yamama
supporting information, p. 2523 - 2526 (2014/05/06)
The dienamine products formed by the reaction between polysubstituted succinimides and the Petasis reagent were subjected to isomerization under mild acidic conditions to give polysubstituted pyrroles in excellent yields (85-95%). The scope and limitations of this methodology are explored.
PROCESS FOR ENANTIOMERIC ENRICHMENT OF 2 ', 6 ' - PIPECOLOXYLIDIDE
-
Page/Page column 17, (2014/02/15)
The invention discloses a process for enantiomeric enrichment of 2',6'-pipecoloxylidide using a chiral carbamoyl benzoic acid to provide (S)-enantiomer in high yield and high enantiomeric purity. The invention also discloses novel intermediates formed in the process of enantiomeric enrichment of 2',6'-pipecoloxylidide, preparation of N- substituted amidic acids and alkylation of 2',6'-pipecoloxylidide.
Use of diamines containing the α-phenylethyl group as chiral ligands in the asymmetric hydrosilylation of prochiral ketones
Mastranzo, Virginia M.,Quintero, Leticia,De Parrodi, Cecilia Anaya,Juaristi, Eusebio,Walsh, Patrick J.
, p. 1781 - 1789 (2007/10/03)
Chiral diamines 1-7 were used in the enantioselective hydrosilylation of prochiral aromatic and aliphatic ketones. Some of these ligands combine chiral backbones and chiral N,N′-α-phenylethyl substituents that give rise to synergistic effects between these two groups and lead to catalysts that exhibit high enantioselectivity.
