21754-31-4

Usage

Uses

Used in Pharmaceutical Industry:
CYCLO(-SER-TYR) is used as a pharmaceutical compound for its broad spectrum of biological activities. Its diverse properties make it a promising candidate for the development of new drugs and therapies.
Used in Natural Products Industry:
CYCLO(-SER-TYR) is used as an active ingredient in the natural products industry, where its biological activities can be harnessed to create health supplements and alternative medicine options.
Used in Research and Development:
CYCLO(-SER-TYR) is utilized as a research compound for studying its various biological activities and potential applications in medicine. This can lead to the discovery of new treatments and advancements in healthcare.

InChI:InChI=1/C12H14N2O4/c15-6-10-12(18)13-9(11(17)14-10)5-7-1-3-8(16)4-2-7/h1-4,9-10,15-16H,5-6H2,(H,13,18)(H,14,17)/t9-,10-/m0/s1

Upstream product

• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 3417-91-2 L-tyrosine methyl ester HCl 
• 3978-80-1 Boc-Tyr-OH 
• 16874-54-7 Boc-Tyr-Ser-OMe 

Downstream Products

• 74347-50-5 phomamide 

Relevant academic research and scientific papers

Synthesis and anti-cancer activity of naturally occurring 2,5-diketopiperazines

Three naturally occurring oxyprenylated diketopiperazines were synthesized and preliminarily tested as growth inhibitory agents in vitro against various cancer cell lines. The compounds were tested on six human cancer cell lines with different sensitivity to proapoptotic stimuli using the MTT colorimetric assay. The data revealed that of the chemicals under study only deoxymicelianamide (11) displayed the highest activity, recording mean IC50 growth inhibitory values ranging from 2 to 23 μM. A comparative study with the non-geranylated saturated derivative of (11) revealed the importance of the presence of the geranyloxy side chain and the exocyclic 2,5-DPK double bond moiety for the observed activity.

AGRICULTURAL CHEMICAL CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT

Disclosed herein is an agricultural agent containing a 2,5-diketopiperazine derivative capable of controlling plant diseases and promoting plant growth or an agriculturally acceptable salt thereof as an active ingredient.

Structure and Synthesis of Phomamide, a New Piperazine-2,5-dione related to the Sirodesmins, isolated from the Culture Medium of Phoma lingam Tode

Several active substances are produced by the fungus Phoma lingam Tode, among which are the previously reported sirodesmins PL (1) and (2), sulphur-containing piperazinediones.A new metabolite, phomamide, also a piperazine-2,5-dione, has now been isolated