2176-63-8

Usage

Uses

Used in Chemical Synthesis:
2,3,5,6-Tetrachloropyridin-4-amine is used as a key intermediate in the synthesis of various organic compounds, such as pesticides and pharmaceuticals. Its presence in these compounds contributes to their biological activity and effectiveness.
Used in Material Science:
Due to its unique chemical properties, 2,3,5,6-Tetrachloropyridin-4-amine has potential applications in the field of material science. It can be utilized in the development of new materials with specific properties, such as enhanced stability or reactivity.
Used in Pesticide Production:
2,3,5,6-Tetrachloropyridin-4-amine is used as a building block in the production of pesticides. Its incorporation into these compounds enhances their pesticidal properties, making them more effective in controlling pests and protecting crops.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 2,3,5,6-Tetrachloropyridin-4-amine is used as a starting material for the development of new drugs. Its unique structure and properties can be leveraged to create pharmaceuticals with specific therapeutic effects.
Safety Precautions:
Given its hazardous nature, 2,3,5,6-Tetrachloropyridin-4-amine should be handled and stored with extreme caution. Proper safety measures, such as wearing protective gear and using appropriate containment systems, should be implemented to minimize the risk of exposure to human health and the environment.

InChI:InChI=1/C5H2Cl4N2/c6-1-3(10)2(7)5(9)11-4(1)8/h(H2,10,11)

Upstream product

• 17325-31-4 2,6-Dihydroxy-4-amino-pyridin 
• 2176-62-7 2,3,4,5,6-pentachloropyridine 
• 28443-69-8 4-amino-2,3,5-trichloropyridine 
• 87052-66-2 2,3,5,6-Tetrachloro-4-pyridylcarbonimidoyl Dichloride 
• 50524-37-3 4-amino-3,5,6-trichloro-pyridin-2-ol 
• 10026-13-8 phosphorus pentachloride 
• 7664-41-7 ammonia 
• 10025-87-3 trichlorophosphate 
• 107-10-8 propylamine 
• 75-31-0 isopropylamine 
• 2808-86-8 2,3,4,5-tetrachloro-pyridine 

Downstream Products

• 87052-69-5 N,N'-Diphenyl-N''-(2,3,5,6-tetrachloro-pyridin-4-yl)-guanidine 

Relevant academic research and scientific papers

Reactions of 4-(dimethylamino)pyridinium activated pentachloropyridine with nitrogen nucleophiles and hydride

Substitution reactions on 2′,3′,5′,6′-tetrachloro-4-dimethylamino-[1,4]bipyridinyl-1-ylium chloride with nitrogen nucleophiles such as n-propylamine, isopropylamine, glycine, morpholine, and piperidine were examined. Highly functionalized Cl2,Cl3,N4,Cl5,Cl6- and N2,Cl3,N4,Cl5,Cl6-substituted pyridines were obtained, in part possessing unsubstituted 4-amino groups due to dealkylation. Detailed NMR studies were performed in order to elucidate the regiochemistry of these dealkylations.

SYNTHESIS AND INTRAMOLECULAR ELECTRON ENTERACTIONS IN TETRACHLORO-4-PYRIDYLCARBONIMIDOYL DICHLORIDE AND ITS DERIVATIVES

Tetrachloro-4-pyridylcarbonimidoyl dichloride was synthesized, and products of the reaction of the latter with amines, triethyl phosphite, and dimethylformamide (DMF) were obtained; acid hydrolysis was also carried out.The character of the intramolecular interactions between the ? system of the pyridine ring and the C=N bond was investigated by IR spectroscopy.

MECHANISM FOR REACTIONS OF HALOGENATED COMPOUNDS. PART 4. ACTIVATING INFLUENCES OF RING-NITROGEN AND TRIFLUOROMETHYL IN NUCLEOPHILIC AROMATIC SUBSTITUTION

Rate constants have been measured for the reactions of ammonia with various fluorinated pyridines and diazines in aqueous dioxan at 25 deg C.From the results the activating effects of ring-nitrogen (relative to C-H) and of trifluoromethyl (relative to -H)