21765-32-2

Upstream product

• 6023-68-3 diethyl-2,2-diphenylsuccinate 
• 141-52-6 sodium ethanolate 
• 14702-32-0 α,α-diphenylsuccinic acid anhydride 
• 33925-43-8 ethyl β-cyano-β,β-diphenylpropionate 
• 10186-26-2 2,2-diphenylsuccinic acid 
• 33925-44-9 β-cyano-β,β-diphenylpropionic acid 

Downstream Products

• 67390-35-6 β,β-Diphenyl-γ-butyrolactone 
• 606-83-7 3,3-Diphenylpropionic acid 
• 179173-57-0 1-[[1-[3,3-Diphenyl-3-(ethoxycarbonyl)propionyl]-4-piperidyl]methyl]-1H-2-methylimidazo[4,5-c]pyridine 

Relevant academic research and scientific papers

(2-Alkyl-3-pyridyl)methylpiperazine derivatives as PAF antagonists

The present invention relates to new (2-alkyl-3-pyridyl) methylpiperazine derivatives of general formula I: wherein R1, R2 and Z are as defined in Claim 1. The invention also relates to processes for their preparation and to pharmaceutical compositions containing them. These compounds are potent, orally active PAF antagonists and, consequently, they are useful in the treatment of the diseases in which this substance is involved.