217659-33-1Relevant academic research and scientific papers
HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES
-
Page/Page column 292, (2018/09/12)
The present invention relates to novel compounds (I) particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for compositions and ophthalmic devices as well as to compositions and ophthalmic devices compri
Toward selective ERβ agonists for central nervous system disorders: Synthesis and characterization of aryl benzthiophenes
Schopfer, Ulrich,Schoeffter, Philippe,Bischoff, Serge F.,Nozulak, Joachim,Feuerbach, Dominik,Floersheim, Philipp
, p. 1399 - 1401 (2007/10/03)
In an effort to identify selective for the estrogen receptor subtype ERβ, a series of aryl benzthiophenes was synthesized. In a radioligand binding assay and reporter gene assat in HeLa and SH-SY5Y cells, compound were characterized as ERβ-selective agonists. By targeting ERβ in the brain, these compounds could lead to drugs able to separate the beneficial effects of estrogens on mood, learning, and memory from side effects such as the stimulation of edometrial and breast cancer.
2-arylbenzo[B]thiophenes useful for the treatment of estrogen deprivation syndrome
-
, (2008/06/13)
This invention provides methods which are useful for the inhibition of the various medical conditions associated with estrogen deprivation syndrome including osteoporosis and hyperlipidemia utilizing compounds of formula I:
