217660-48-5

Upstream product

• 95-46-5 2-methylphenyl bromide 
• 217660-37-2 2-trimethylstannyl-6-methoxybenzo[b]thiophene 
• 183133-90-6 2-bromo-6-methoxybenzo[b]thiophene 
• 16419-60-6 2-Methylphenylboronic acid 
• 90560-10-4 6-methoxy-benzo[b]thiophene 
• 96803-85-9 1-[(2,2-diethoxyethyl)sulfanyl]-3-methoxybenzene 
• 15570-12-4 3-methoxybenzenethiol 

Relevant academic research and scientific papers

ESTROGEN RECEPTOR-MODULATING COMPOUNDS

Described herein are compounds that are estrogen receptor modulators of formula I' Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Synthesis of estradiol backbone mimics via the Stille reaction using copper(II) oxide as co-reagent

Sterically hindered biaryls and 2-phenylbenzo[b]thiophenes that can serve as templates for mimics of the estradiol backbone were prepared in modest to good yields by the Stille reaction using CuO as a co-reagent. Due to the neutral conditions applied in t