21778-79-0Relevant academic research and scientific papers
Improved Preparation of N-Propargyl-2-(5-benzyloxyindolyl)methylamine [a]
Marco, Jose L.
, p. 475 - 476 (1998)
An improved synthetic sequence for the synthesis of N-propargyl-2-(5-benzyloxyindolyl)methylamine (1) is described.
N-methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor
Bautista-Aguilera, Oscar M.,Samadi, Abdelouahid,Chioua, Mourad,Nikolic, Katarina,Filipic, Slavica,Agbaba, Danica,Soriano, Elena,De Andrés, Lucía,Rodríguez-Franco, María Isabel,Alcaro, Stefano,Ramsay, Rona R.,Ortuso, Francesco,Ya?ez, Matilde,Marco-Contelles, José
supporting information, p. 10455 - 10463 (2015/02/19)
On the basis of N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine (II, ASS234) and QSAR predictions, in this work we have designed, synthesized, and evaluated a number of new indole derivatives from which we have identified N-methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine (2, MBA236) as a new cholinesterase and monoamine oxidase dual inhibitor.
SUBSTITUTED DIHYDROPYRANO INDOLE-3,4-DIONE DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1)
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Page 29, (2010/02/07)
Compounds of formula (1) and II) are provided wherein: X is an alkali metal or a basic amine moiety; R1, is alkyl, cycloalkyl, -CH2--cycloalkyl, pyridinyl, -CH2-pyridinyl, phenyl or benzyl, the rings of these gr
Synthesis of 2'-[2-(5-benzyloxyindolyl)]propylamine derivatives
Marco, Jose L.,Martin, Gema
, p. 921 - 926 (2007/10/03)
The synthesis of some 2'-[2-(5-benzyloxyindolyl)]propylamine derivatives 1-15 from 2-(5-benzyloxyindole)carboxyaldehyde (16) and 2-(5-benzyloxy-1-methylindole) carboxyaldehyde (17) is reported. Compounds 1-15 have been designed as potential monoamine oxid
