21778-83-6

Upstream product

• 24985-85-1 ethyl 5-hydroxyindole-2-carboxylate 
• 21598-06-1 5-hydroxyindole-2-carboxylic acid 
• 4382-54-1 5-methoxy-1H-indole-2-carboxylic acid 
• 6640-09-1 5-benzyloxy-1H-indole-2-carboxylic acid 
• 37033-95-7 5-benzyloxy-1H-indole-2-carboxylic acid ethyl ester 
• 21778-79-0 (5-(benzyloxy)-1H-indol-2-yl)methanol 

Downstream Products

• 95094-64-7 5-Benzyloxy-1H-indole-2-carbaldehyde oxime 
• 133845-63-3 N-((5-(benzyloxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine 
• 622863-80-3 5-(benzyloxy)-2-[(E)-2-(2-methoxy-4-nitrophenyl)ethenyl]-1H-indole 
• 1262007-78-2 2-(10-chloro-8-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-2-methyl-1,2,3,4-tetrahydropyrazino[1,2-a]indol-1-yl)acetic acid 
• 1262007-77-1 2-(10-chloro-8-(3-cyano-5-(trifluoromethoxy)benzyloxy)-2-methyl-1,2,3,4-tetrahydropyrazino[1,2-a]indol-1-yl)acetic acid 
• 1262007-61-3 2-(8-(4-isopropoxy-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydropyrazino[1,2-a]indol-1-yl)acetic acid 
• 1262007-60-2 2-(10-chloro-8-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-3,4-dihydro-1H-[1,4]oxazino[4,3-a]indol-1-yl)acetic acid 
• 1262007-64-6 2-(10-chloro-8-(3-cyano-4-isopropoxybenzyloxy)-3,4-dihydro-1H-[1,4]oxazino[4,3-a]indol-1-yl)acetic acid 
• 1262007-63-5 2-(10-chloro-8-(4-isopropoxy-3-(trifluoromethyl)benzyloxy)-3,4-dihydro-1H-[1,4]oxazino[4,3-a]indol-1-yl)acetic acid 
• 1262007-68-0 2-(8-(3-chloro-4-(1,3-difluoropropan-2-yloxy)benzyloxy)-3,4-dihydro-1H-[1,4]oxazino[4,3-a]indol-1-yl)acetic acid 
• 1262007-55-5 2-(8-(3-cyano-4-isopropoxybenzyloxy)-3,4-dihydro-1H-[1,4]oxazino[4,3-a]indol-1-yl)acetic acid 
• 1262007-67-9 2-(8-(4-(fluoromethoxy)-3-(trifluoromethyl)benzyloxy)-3,4-dihydro-1H-[1,4]oxazino[4,3-a]indol-1-yl)acetic acid 
• 1262007-59-9 2-(8-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-3,4-dihydro-1H-[1,4]oxazino[4,3-a]indol-1-yl)acetic acid 
• 1262007-76-0 2-(8-(3-cyano-5-(trifluoromethoxy)benzyloxy)-3,4-dihydro-1H-[1,4]oxazino[4,3-a]indol-1-yl)acetic acid 

Relevant academic research and scientific papers

AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE

Relating to a compound represented by formula (I) and a pharmaceutically acceptable salt of the compound, and an application of the compound as an S1P1 agonist.

Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water Solubility

Indolecarboxamides are potent but poorly soluble mycobactericidal agents. Here we found that modifying the incipient scaffold by amide-amine substitution and replacing the indole ring with benzothiophene or benzoselenophene led to striking (10-20-fold) im

Synthesis of 2'-[2-(5-benzyloxyindolyl)]propylamine derivatives

The synthesis of some 2'-[2-(5-benzyloxyindolyl)]propylamine derivatives 1-15 from 2-(5-benzyloxyindole)carboxyaldehyde (16) and 2-(5-benzyloxy-1-methylindole) carboxyaldehyde (17) is reported. Compounds 1-15 have been designed as potential monoamine oxid

Improved Preparation of N-Propargyl-2-(5-benzyloxyindolyl)methylamine [a]

An improved synthetic sequence for the synthesis of N-propargyl-2-(5-benzyloxyindolyl)methylamine (1) is described.