217964-22-2Relevant academic research and scientific papers
The thionium/N-acyliminium ion cyclization cascade as a strategy for the synthesis of azapolycyclic ring systems
Padwa, Albert,Waterson, Alex G.
, p. 10159 - 10173 (2007/10/03)
A series of amidosulfoxides were prepared by the addition of thiophenol to the appropriate alkenoic acid π-bond, and this was followed by reaction of the in situ generated acyl chloride with 3,4-dimethoxyphenethyl amine. The silicon-induced Pummerer react
Synthesis of the Perhydroindole Nucleus by a Pummerer/Mannich Induced Cyclization Cascade
Pawda, Albert,Waterson, Alex G.
, p. 8585 - 8588 (2007/10/03)
The silicon-induced Pummerer reaction of several amido sulfoxydes possessing tethered ?-bonds proceeds by way of a thionium/N-acyliminium ion cascade to provide various azabicyclic ring systems.This cascade sequence was applied toward the synthesis of a member of the protoberberine alkaloid family.
