17742-53-9

Upstream product

• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 
• 108-98-5 thiophenol 
• 930-69-8 sodium thiophenolate 
• 4551-15-9 phenylthiotrimethylsilane 
• 855659-26-6 diethyl 2-(3-(phenylthio)propyl)malonate 
• 24536-40-1 3-phenylthiopropanol 
• 3238-98-0 3-phenylthio-1-bromopropane 
• 1119-46-6 5-chloro-valeric acid 
• 855659-27-7 (3-phenylsulfanyl-propyl)-malonic acid 

Downstream Products

• 77734-62-4 6-Phenylsulfanyl-tetrahydro-pyran-2-one 
• 343941-84-4 5-phenylsulfanyl-valeryl chloride 
• 328058-71-5 N-[2-(1-benzyl-1H-indol-3-yl)ethyl]-5-(phenylsulfanyl)pentanamide 
• 328058-69-1 N-[2-(3,4-dimethoxyphenyl)ethyl]-5-(phenylsulfanyl)pentanamide 
• 328058-60-2 5-benzenesulfinyl-N-(2-(cyclohex-1-enyl)ethyl)pentanamide 
• 328058-73-7 N-(2-(cyclohex-1-enyl)ethyl)-5-(phenylsulfanyl)pentanamide 
• 328058-61-3 1-(2-(cyclohex-1-enyl)ethyl)-6-(phenylsulfanyl)piperidin-2-one 
• 328058-64-6 N-(3-bromobut-3-enyl)-5-(benzenesulfinyl)pentanamide 
• 328058-77-1 N-(3-bromobut-3-enyl)-5-(phenylsulfanyl)pentanamide 
• 145471-55-2 12-benzyl-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizine-4-one 
• 217964-22-2 1-[2-(1-benzyl-1H-indol-3-yl)ethyl]-6-phenylsulfanylpiperidin-2-one 
• 217964-20-0 5-benzenesulfinyl-N-[2-(1-benzyl-1H-indol-3-yl)ethyl]pentanamide 
• 217964-16-4 N-[2-(3,4-dimethoxyphenyl)ethyl]-5-(benzenesulfinyl)pentanamide 
• 217964-18-6 1-[2-(3,4-dimethoxyphenyl)ethyl]-6-phenylsulfanyl-piperidin-2-one 

Relevant academic research and scientific papers

Synthesis of a wide range of thioethers by indium triiodide catalyzed direct coupling between alkyl acetates and thiosilanes

An indium triiodide-catalyzed substitution of the acetoxy group in alkyl acetates with thiosilanes provides access to a variety of thioethers. The method is efficient for a wide scope of acetates such as primary alkyl, secondary alkyl, tertiary alkyl, allylic, benzylic, and propargylic acetates.

AN IMPROVED PROCESS FOR THE PREPARATION OF VALSARTAN

The present invention relates to an improved process for the preparation of valsartan compound of formula-1 through novel intermediate compounds. It also relates to a novel process for the preparation of amorphous form of valsartan.

CONVERSION OF LACTONE INTO LACTONE HEMITHIOACETAL AND SYNTHESIS OF ENOL LACTONE

Lactone hemithioacetal was synthesized in good yield from ω-phenylthiocarboxylic acid derived from lactone, and it was converted into enol lactone via the corresponding sulfoxide.

Hard Acid and Soft Nucleophile Systems. 5. Ring-Opening Reaction of Lactones to ω-Alkylthio or ω-Arylthio Carboxylic Acids with Aluminum Halide and Thiol

Lactones were converted into ω-alkylthio carboxylic acids in high yields through ω-carbon-oxygen bond cleavage when they were treated with aluminun halide and alkanethiol.The aluminum halide and arenethiol system has also been found to be useful for the preparation of the synthetically valuable ω-arylthio carboxylic acids from lactones.