218-38-2

Basic information

• Product Name: 5-Azachrysene
• Synonyms: 5-Azachrysene
• CAS NO: 218-38-2
• Molecular Formula: C₁₇H₁₁N
• Molecular Weight: 229.27594
• Mol File: 218-38-2.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 449.7°Cat760mmHg
• Flash Point: 203.2°C
• Appearance: /
• Density: 1.239g/cm³
• Vapor Pressure: 7.47E-08mmHg at 25°C
• Refractive Index: 1.783
• CAS DataBase Reference: 5-Azachrysene(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Azachrysene(218-38-2)
• EPA Substance Registry System: 5-Azachrysene(218-38-2)

Safety Data

• Hazardous Substances Data: 218-38-2(Hazardous Substances Data)

Usage

General Description

5-Azachrysene is a polycyclic aromatic hydrocarbon (PAH) with a chemical structure that consists of a five-membered nitrogen-containing ring fused to a six-membered carbon ring. It is a highly toxic and carcinogenic compound that has been shown to induce DNA damage and mutations in bacteria and mammalian cells. 5-Azachrysene is considered a potent environmental and occupational carcinogen, and exposure to this chemical has been linked to an increased risk of lung and skin cancer. It is commonly found in industrial pollutants, cigarette smoke, and vehicle exhaust, making it a significant concern for public health and environmental safety. Research on the toxicological effects and potential regulatory measures for 5-Azachrysene is ongoing in order to minimize its impact on human health and the environment.

InChI:InChI=1/C17H11N/c1-4-8-15-12(5-1)9-10-16-14-7-3-2-6-13(14)11-18-17(15)16/h1-11H

Upstream product

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• 18271-17-5 N-tosyl-1-naphthylamine 
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• 223575-47-1 2-(naphthalen-2’-yl)benzaldehyde 

Relevant articles and documents

A new synthetic approach to the benzo[c]phenanthridine ring system

The base-catalyzed reaction of 2-methylbenzonitrile and paraformaldehyde provided 6-amino-11,12-dihydrobenzo[c]phenanthridine, which was converted via the corresponding 6-oxo- and 6-thioxo-derivatives into benzo[c]phenanthridine.

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STUDIES ON THE ALKALOIDS OF PAPAVERACEAE. VI. ALKALOIDS OF CORYDALIS

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Sanguinarine as a new chemical entity of thioredoxin reductase inhibitor to elicit oxidative stress and promote tumor cell apoptosis

The alteration of redox homeostasis is a hallmark of cancer cells. As a critical player in regulating cellular redox signaling, thioredoxin reductase (TrxR) enzymes are increasingly recognized as attractive targets for anticancer drug development. We repo

Synthesis method of phenanthridine and derivative of phenanthridine

The invention discloses a synthesis method of phenanthridine as shown in a formula (I) and a derivative of the phenanthridine. In the synthesis method, o-arylphenylsulfimide shown as a formula (II) isused as a raw material and reacts in an organic solvent under the action of a [Cu]/Selectfluor catalyst to obtain a corresponding target product (I). The synthesis method disclosed by the invention has the advantages of cheap and easily available and low-toxicity catalyst, environmental friendliness, mild reaction conditions, high universality of functional group and easiness and convenience in operation. The formulas (I) and (II) are shown in the description.