218145-71-2

Upstream product

• 50299-15-5 allylglycine methyl ester 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 67-56-1 methanol 
• 1069-48-3 rac-allylglycine 

Downstream Products

• 869896-61-7 methyl 5-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-1-[(4-nitrophenyl)sulfonyl]-1,2,3,6-tetrahydropyridine-2-carboxylate 
• 869896-60-6 methyl 1-[(4-nitrophenyl)sulfonyl]-5-phenyl-1,2,3,6-tetrahydropyridine-2-carboxylate 
• 869896-63-9 methyl 5-phenyl-1,2,3,6-tetrahydropyridine-2-carboxylate 
• 869896-58-2 methyl 2-{[2-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)prop-2-enyl][(4-nitrophenyl)sulfonyl]amino}pent-4-enoate 
• 869896-59-3 methyl 2-{[(4-nitrophenyl)sulfonyl][2-(1-methyl-2,3-dioxo-2,3-dihydro-1H-indol-5-yl)prop-2-enyl]amino}pent-4-enoate 
• 869896-57-1 methyl 2-{[(4-nitrophenyl)sulfonyl](2-phenyl-prop-2-enyl)amino}pent-4-enoate 
• 252648-31-0 2-[ethynyl-(4-nitro-benzenesulfonyl)-amino]-pent-4-enoic acid methyl ester 

Relevant academic research and scientific papers

Δ3-Aryl/heteroaryl substituted heterocycles via sequential Pd-catalysed termolecular cascade/ring closing metathesis (RCM)

A novel sequential Pd-catalysed termolecular allenylation cascade/Ru catalysed RCM process affords a diverse range of Δ3-aryl/ heteroaryl substituted five-seven membered nitrogen and oxygen heterocycles. Further elaboration, via 1,3-dipolar cyc

Stereospecific synthesis of chiral N-(ethynyl)allylglycines and their use in highly stereoselective intramolecular Pauson-Khand reactions

The first synthesis of an enantiopure N-ethynylated allylglycine and its application in the intramolecular Pauson-Khand reaction, which leads to a novel highly functionalised proline derivative with complete control of stereoselectivity, is reported.