218167-54-5Relevant articles and documents
Selectivity of inhibition of matrix metalloproteases MMP-3 and MMP-2 by succinyl hydroxamates and their carboxylic acid analogues is dependent on P3′ group chirality
Fray,Burslem,Dickinson, RogerP
, p. 567 - 570 (2007/10/03)
Structure-activity relationships are described for a series of succinyl hydroxamic acids 1a-o and their carboxylic acid analogues 2a-o as inhibitors of matrix metalloproteases MMP-3 and MMP-2. For this series (P1′=(CH2)3Ph, P′2=t-Bu)