2182-39-0

Basic information

• Product Name: 2-PhenylaMino-propionitrile
• Synonyms: 2-(Phenylamino)propanenitrile; n-propyl β-D-glucopyranoside; 2-anilinopropionitrile; N-Phenyl-alanin-nitril; beta-anilinopropionitrile; N-cyanoethylaniline; anilinopropionitrile; 查看更多英文别名 收起
• CAS NO: 2182-39-0
• Molecular Formula: C₉H₁₀N₂
• Molecular Weight: 146.1891
• EINECS: -0
• Mol File: 2182-39-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 92 °C(Solv: benzene (71-43-2))
• Boiling Point: 304.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.077±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 1.70±0.50(Predicted)
• CAS DataBase Reference: 2-PhenylaMino-propionitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PhenylaMino-propionitrile(2182-39-0)
• EPA Substance Registry System: 2-PhenylaMino-propionitrile(2182-39-0)

Safety Data

• Hazardous Substances Data: 2182-39-0(Hazardous Substances Data)

Usage

General Description

2-Phenylamino-propionitrile, also known as N-(2-Phenylethyl)propionitrile, is a chemical compound with the molecular formula C9H10N2. It is an organic compound that consists of a phenyl group attached to an amino group and a propionitrile group. 2-PhenylaMino-propionitrile is commonly used in the pharmaceutical industry as a building block in the synthesis of various drugs and chemicals. It can also be used as a reagent in organic synthesis and as a precursor to other chemical compounds. 2-Phenylamino-propionitrile is an important intermediate in the production of pharmaceuticals and is used in the synthesis of various products, including anti-depressant drugs.

Upstream product

• 74-90-8 hydrogen cyanide 
• 75-07-0 acetaldehyde 
• 62-53-3 aniline 
• 60-29-7 diethyl ether 
• 107-13-1 acrylonitrile 
• 19481-82-4 2-bromopropionitrile 
• 631-57-2 Acetyl cyanide 
• 143-33-9 sodium cyanide 
• 78-97-7 2-hydroxy-propionitrile 
• 6052-11-5 N-ethylideneaniline 
• 5919-63-1 N,N'-diphenyl-ethylidenediamine 

Downstream Products

• 35118-25-3 N-(Cyano-methyl-methyl)-2-nitro-N-phenyl-benzamide 
• 154319-63-8 N-Phenyl-N-(α-cyanoethyl)-p-fluorobenzamide 
• 74-90-8 hydrogen cyanide 
• 142-04-1 aniline hydrochloride 
• 105510-39-2 N-(2-propionitrile)-N-phenylcarbamoyl chloride 
• 42164-53-4 (-)-N²-phenyl-propane-1,2-diamine 
• 42164-53-4 (+)-N²-phenyl-propane-1,2-diamine 
• 15727-49-8 N-Phenylalanin 
• 5813-88-7 2-(phenylamino)propanamide 
• 2182-37-8 N-<1-Cyan-aethyl>-N-phenyl-2-chlor-propionsaeure-amid 
• 2412-47-7 N-<1-Cyan-aethyl>-N-phenyl-chloressigsaeure-amid 
• 85599-78-6 Phenyl-trimethylsilanyl-((E)-2-trimethylsilanyl-vinyl)-amine 

Relevant articles and documents

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Controllable access to multi-substituted imidazoles: Via palladium(II)-catalyzed C-C coupling and C-N condensation cascade reactions

A novel and efficient protocol for the synthesis of various 2,4-disubstituted, 1,2,4-trisubstituted and 1,2,4,5-tetra-substituted imidazoles via cascade palladium catalyzed C-C coupling followed by intramolecular C-N bond formation was developed. Readily accessible boronic acids and N-substituted-2-aminoacetonitriles were firstly reported as starting materials to construct di-, tri-, and tetra-substituted imidazoles in good to excellent yield.

Benzofuran derivatives and their use as antibacterial agents

The invention relates to novel benzofuran derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as anti-infectives.