21821-40-9

Basic information

• Product Name: 4-(5-FORMYL-2-FURYL)BENZENE-1-SULFONAMIDE
• Synonyms: 4-(5-FORMYL-2-FURYL)BENZENE-1-SULFONAMIDE;AKOS BB-8350;2-Formyl-5-(4-sulphamoylphenyl)furan, 5-[4-(Aminosulphonyl)phenyl]-2-furaldehyde;4-(5-Formylfur-2-yl)benzenesulphonamide;TIMTEC-BB SBB000902;ART-CHEM-BB B025368;ASISCHEM S89480;AURORA KA-4223
• CAS NO: 21821-40-9
• Molecular Formula: C₁₁H₉NO₄S
• Molecular Weight: 251.26
• Mol File: 21821-40-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 199 °C
• Boiling Point: 493.1 °C at 760 mmHg
• Flash Point: 252 °C
• Appearance: /
• Density: 1.41 g/cm³
• Vapor Pressure: 7.26E-10mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: 4-(5-FORMYL-2-FURYL)BENZENE-1-SULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-FORMYL-2-FURYL)BENZENE-1-SULFONAMIDE(21821-40-9)
• EPA Substance Registry System: 4-(5-FORMYL-2-FURYL)BENZENE-1-SULFONAMIDE(21821-40-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 21821-40-9(Hazardous Substances Data)

Usage

General Description

4-(5-Formyl-2-furyl)benzene-1-sulfonamide is a chemical compound that belongs to the class of sulfonamide derivatives. It is a white to yellow powder with potential pharmaceutical properties. 4-(5-FORMYL-2-FURYL)BENZENE-1-SULFONAMIDE has been studied for its potential use in medicinal chemistry, particularly in the development of drugs with antibacterial, antiviral, and anti-inflammatory properties. Its structure containing a furan ring and sulfonamide group makes it a promising candidate for drug development. Additionally, it may have potential applications in research for the treatment of various diseases and as a building block for the synthesis of novel pharmaceutical compounds.

InChI:InChI=1/C11H9NO4S/c12-17(14,15)10-4-1-8(2-5-10)11-6-3-9(7-13)16-11/h1-7H,(H2,12,14,15)

Upstream product

• 1899-24-7 5-bromo-2-furancarboxaldehyde 
• 613660-87-0 4-sulfamoylphenylboronic acid 
• 27329-70-0 5-formylfurane-2-boronic acid 
• 701-34-8 4-bromo-benzenesulfonic acid amide 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 98-01-1 furfural 
• 35282-78-1 4-(aminosulphonyl)benzenediazonium chloride 

Downstream Products

• 1619995-17-3 4-{5-[(E)-(naphthalen-2-ylimino)methyl]furan-2-yl}benzenesulfonamide 
• 1619995-06-0 4-[5-(9,9-dimethyl-11-oxo-7,8,9,10,11,12-hexahydrobenzo[a]acridin-12-yl)furan-2-yl]benzenesulfonamide 
• 441718-16-7 methyl 4-(3,5-dioxo-4-((5-(4-sulfamoylphenyl)furan-2-yl)methylene)pyrazolidin-1-yl)benzoate 
• 336178-16-6 C₂₂H₁₇N₃O₆S 
• 765938-44-1 3-[5-(4-aminosulfonylphenyl)-2-furyl]acrylic acid 

Relevant articles and documents

Acrylamide derivative and preparation method and application thereof

The invention belongs to the field of chemical medicines, and particularly relates to an acrylamide derivative. The acrylamide derivative adopts a structural general formula as follows: FORMULA. Someembodiments of the acrylamide derivative confirm that th

Discovery of new Gram-negative antivirulence drugs: Structure and properties of novel E. coli WaaC inhibitors

Heptosyltransferases such as WaaC represent promising and attractive targets for the discovery of new Gram-negative antibacterial drugs based on antivirulence mechanisms. We report herein our approach to the identification of the first micromolar inhibitors of WaaC and the preliminary SAR generated from this family of 2-aryl-5-methyl-4-(5-aryl-furan-2-yl-methylene)-2,4-dihydro-pyrazol-3-on es identified by virtual screening.

Structure-activity relationships of novel anti-malarial agents. Part 7: N-(3-benzoyl-4-tolylacetylaminophenyl)-3-(5-aryl-2-furyl)acrylic acid amides with polar moieties

In a previous report, we have provided evidence that novel anti-malarial compounds based on 2,5-diaminobenzophenone farnesyltransferase inhibitors might benefit from the presence of a polar moiety at the para position of the terminal phenyl of the arylfur