21825-19-4Relevant academic research and scientific papers
Anti-allergic oxanilate compounds
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, (2008/06/13)
A method of treating mammals for allergy and anaphylactic reactions of a reagin or non-reagin mediated nature which comprises administering prophylactically to said mammal an anti-allergy or anaphylactic reaction effective amount of a compound of the formula STR1 Novel compounds and compositions are also claimed.
Oxanilic acids, a new series of orally active antiallergic agents
Sellstedt,Guinosso,Begany,Bell,Rosenthale
, p. 926 - 933 (2007/10/05)
A large number of oxanilic acid esters and N heteroaryl oxamic acid esters were prepared and found to have antiallergic activity using the rat passive cutaneous anaphylaxis (PCA) test. Many of the oxanilic acid esters are active orally, with the most active species having an aryl 2' carbamoyl group and a 3' methoxy group. Hydrolysis of the ester from the oxanilic ester moiety causes a loss of oral activity.
