218301-87-2

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
4-N-Boc-amino-3-fluorophenylboronic acid is utilized as a key building block for the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows for the creation of diverse chemical entities with potential therapeutic and pesticidal properties.
Used in Material and Catalyst Development:
In the field of material science, 4-N-Boc-amino-3-fluorophenylboronic acid is employed as a component in the development of new materials with specific properties. Its ability to form stable complexes with diols makes it suitable for the construction of organic frameworks. Additionally, it is used in the development of catalysts that facilitate various chemical reactions.
Used in Biomolecule Functionalization:
4-N-Boc-amino-3-fluorophenylboronic acid is used as a selective functionalization agent for biomolecules. Its reactivity allows for the attachment of functional groups to biomolecules without affecting their native structure and function, which is crucial in the development of bioconjugates and other bioactive compounds.
Used in Chemical Transformations:
The presence of the Boc protecting group in 4-N-Boc-amino-3-fluorophenylboronic acid enables the compound to undergo various chemical transformations while maintaining its stability and reactivity. This feature is particularly useful in the synthesis of complex organic molecules and the development of novel chemical processes.

InChI:InChI=1/C11H15BFNO4/c1-11(2,3)18-10(15)14-9-5-4-7(12(16)17)6-8(9)13/h4-6,16-17H,1-3H3,(H,14,15)

Upstream product

• 367-24-8 4-bromo-2-fluoroaniline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 209958-42-9 tert-butyl N-(4-bromo-2-fluorophenyl)carbamate 
• 121-43-7 Trimethyl borate 

Downstream Products

• 218301-88-3 2-Fluoro-4-(2-methyl-imidazol-1-yl)-phenylamine 
• 1075189-04-6 tert-butyl 4-(2-(1-ethyl-4-hydroxypiperidin-4-yl)thiazol-5-yl)-2-fluorophenylcarbamate 
• 1093628-98-8 O-[tert-Butyl] N-[2-fluoro-4-(1-methyl-2-oxo-1,2-dihydropyridin-3-yl)phenyl]carbamate 
• 819058-34-9 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 
• 1374109-76-8 C₂₂H₂₄FN₃O₂ 
• 1374107-85-3 2-(4-amino-3-fluorophenyl)-6-dimethylaminoquinoline 
• 1374109-75-7 C₂₂H₂₂FN₃O₃ 
• 1448987-73-2 [4-(6-ethyl-8,8-dimethyl-2-methylsulfanyl-5-oxo-5,6,7,8-tetrahydro-9-oxa-1,3,6-triazabenzocyclohepten-4-yl)-2-fluorophenyl]carbamic acid tert-butyl ester 
• 1276129-51-1 tert-butyl {4-[1-(4-chlorobenzyl)-4-oxo-1,4-dihydrothieno[3,2-d]pyrimidin-6-yl]-2-fluorophenyl}carbamate 
• 1276129-75-9 N-{4-[1-(4-chloro-benzyl)-4-oxo-1,4-dihydro-thieno[3,2-d]pyrimidin-6-yl]-2-fluoro-phenyl}-benzamide 
• 1233692-95-9 tert-butyl 3-fluoro-4'-[2-methyl-1-(pyridin-4-yl)prop-1-enyl]biphenyl-4-ylcarbamate 
• 912954-82-6 1,1-dimethylethyl [4-(2,2-difluoro-1,3-benzodioxol-5-yl)-2-fluorophenyl]carbamate 
• 262444-42-8 tert-butyl N-[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate 

Relevant academic research and scientific papers

Substituted sulphoximines as Tie2 inhibitors and salts thereof, pharmaceutical compositions comprising the same, methods of preparing the same and uses of the same

The invention relates to substituted sulphoximines according to the general formula (I): in which A, E, G, X, R1, R2, R3, R4, R5, R6, R7, R8, m, p, q, are given in the

SULFONAMIDO-MACROCYCLES AS TIE2 INHIBITORS AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME

The invention relates to sulfonamido-macrocycles according to the general formula (I): in which R1, R2, R4, R5, R6, A, B, C, L, X, Y, Z, n, and m are as defined in the claims, and salts, N-oxides, or

NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS

The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula (I) or pharmaceutically acceptable salt forms thereof, wherein rings D-E represent guanidine mimics, which are useful as inhibitors of factor Xa.

Guanidine mimics as factor Xa inhibitors

The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula I: or pharmaceutically acceptable salt forms thereof, wherein rings D—E represent guanidine mimics, which are useful as inhibitors of factor Xa.