2184-00-1

Usage

Uses

Used in Chemical Synthesis Industry:
Benzenediacetimide is used as an intermediate in chemical synthesis for the production of dyes, pigments, and pharmaceuticals. Its unique chemical structure allows it to be a versatile building block in the synthesis of various compounds.
Used in Plastics Industry:
Benzenediacetimide is used as a heat stabilizer in PVC resins. Its ability to withstand high temperatures and resist degradation makes it an essential component in the manufacturing of PVC products.
Used in Photographic Industry:
Benzenediacetimide is used in the manufacture of photographic chemicals. Its properties make it suitable for use in the development and processing of photographic films and papers.
Used in Electronics and Electrical Industry:
Benzenediacetimide is used as a stabilizer in electronic and electrical equipment. Its heat resistance and chemical stability contribute to the longevity and performance of these devices.
It is important to handle benzenediacetimide with caution, as it may cause irritation to the skin, eyes, and respiratory system. Proper safety measures should be taken during its use and handling.

Upstream product

• 7500-54-1 o-xylylenediamide 
• 7500-53-0 1,2-Phenylenediacetic acid 

Downstream Products

• 15987-50-5 1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one 
• 15299-53-3 3-(toluene-4-sulfonyl)-2,3,4,5-tetrahydro-1H-benz[d]azepine 

Relevant academic research and scientific papers

Formamide, a novel challenging reagent for the direct synthesis of non-N-substituted cyclic imides

Aliphatic and aromatic cyclic imides have been prepared in high to moderate yields from cyclic carboxylic anhydrides or corresponding dicarboxylic acids, using formamide as reagent at 170-180°C for 5-6 hours. In the case of aromatic products with lower solubility in formamide, we used N-methyl-2-pyrrolidinone (NMP) as supplementary solvent, which facilitates the reaction.

COMPOUNDS HAVING AFFINITY FOR DOPAMINE D3 RECEPTOR AND USES THEREOF

Compounds of formula (I) and salts thereof are disclosed: wherein A, R1, m, R2, n, R3, R4, q, W1, W2, R5 and R6 are as defined in the description. Methods of preparing the compounds and uses thereof in medicine, for example in the treatment of schizophrenia or drug dependency, are also disclosed.

An expeditious synthesis of cyclic imides

Trifluoroacetamide was reacted with diacids in the presence of N-ethyl- N-dimethylaminopropylcarbodiimide and of 1-hydroxybenzotriazole to afford cyclic imides of different ring size, providing a single step asymmetric synthesis of thalidomide.

(2H)-3-benzazepin-2-ones, their pharmaceutical compositions and their pharmaceutical uses

The invention relates to new heteroaromatic amine derivatives of formula STR1 wherein A represents a --CH2 --CH2 --, --CH=CH--or STR2 group and B represents a methylene, carbonyl or thiocarbonyl group or A represents a --CO--CO or STR3 group and B represents a methylene group, in which the carbon atom marked x is linked to the phenyl nucleus, E represents a straight-chained alkylene group optionally substituted by an alkyl group, G represents a straight-chained alkylene group optionally substituted by an alkyl group, R1 represents a hydrogen, fluorine, chlorine or bromine atom, a trifluoromethyl, nitro, amino, alkylamino, dialkylamino, alkyl, alkylmercapto, hydroxy, alkoxy or phenylalkoxy group, R2 represents a hydrogen, chlorine or bromine atom or a hydroxy, alkoxy, phenylalkoxy or alkyl group or R1 and R2 together represent an alkylenedioxy group, R3 represents a hydrogen atom, an alkenyl group, an alkyl or phenylalkyl group, and Het represents a 5- or 6-membered heteroaromtic ring bonded via a carbon or nitrogen atom, which contains an oxygen, sulphur or nitrogen atom, two nitrogen atoms or a nitrogen atom and an oxygen or sulphur atom, and onto which additionally a phenyl ring can be condensed, in which case the bond can also be via the phenyl nucleus, or an imidazo[1,2-a]pyridyl group wherein the carbon structure of the above-mentioned groups can be substituted by a methylenedioxy or ethylenedioxy group or can be mono- or disubstituted by a halogen atom or an alkyl, hydroxy, alkoxy, phenylalkoxy, phenyl, dimethoxyphenyl, nitro, amino, acetylamino, carbamoylamino, N-alkyl-carbamoylamino, hydroxymethyl, mercapto, alkylmercapto, alkylsulphinyl, alkylsulphonyl, alkylsulphonyloxy, alkylsulphonylamino, alkoxycarbonylmethoxy, carboxymethoxy or alkoxymethyl group, and at the same time any imino group present in the above-mentioned heteroaromatic groups can be substituted by an alkyl, phenylalkyl or phenyl group, the N-oxides and the acid addition salts thereof with inorganic or organic acids, which have valuable pharmacological properties, particularly the effect of lowering heart rate and oxygen requirement of the heart. They can be used to treat sinus tachycardia or ischaemic heart disease.