218431-74-4

Basic information

• Product Name: {(S)-2-[((3R,4R)-1,4-Dibenzyl-pyrrolidine-3-carbonyl)-amino]-4-methyl-pentanoylamino}-acetic acid ethyl ester
• Synonyms: {(S)-2-[((3R,4R)-1,4-Dibenzyl-pyrrolidine-3-carbonyl)-amino]-4-methyl-pentanoylamino}-acetic acid ethyl ester
• CAS NO: 218431-74-4
• Molecular Weight: 493.646
• Mol File: 218431-74-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(S)-2-[((3R,4R)-1,4-Dibenzyl-pyrrolidine-3-carbonyl)-amino]-4-methyl-pentanoylamino}-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {(S)-2-[((3R,4R)-1,4-Dibenzyl-pyrrolidine-3-carbonyl)-amino]-4-methyl-pentanoylamino}-acetic acid ethyl ester(218431-74-4)
• EPA Substance Registry System: {(S)-2-[((3R,4R)-1,4-Dibenzyl-pyrrolidine-3-carbonyl)-amino]-4-methyl-pentanoylamino}-acetic acid ethyl ester(218431-74-4)

Safety Data

• Hazardous Substances Data: 218431-74-4(Hazardous Substances Data)

Upstream product

• 53375-57-8 H-Leu-Gly-OEt 
• 218431-84-6 Methanesulfonic acid (3R,4S)-1,4-dibenzyl-pyrrolidin-3-yl ester 
• 218431-87-9 (3R,4R)-1,4-Dibenzyl-pyrrolidine-3-carboxylic acid 
• 218431-85-7 (3S,4R)-1,4-Dibenzyl-pyrrolidine-3-carbonitrile 

Downstream Products

• 218431-75-5 (3R,4R)-1,4-Dibenzyl-pyrrolidine-3-carboxylic acid [(S)-1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide 

Relevant articles and documents

β-analogs of PLG (L-prolyl-L-leucyl-glycinamide): Ex-chiral pool syntheses and dopamine D2 receptor modulating effects

Starting from (S)- and (R)-aspartic acid enantiomerically pure β- proline derivatives were synthesized. These chiral building blocks were transformed into β-analogs of the dopamine receptor modulating peptide PLG. According to dopamine receptor binding st