53375-57-8Relevant academic research and scientific papers
Circular dichroism studies on absolute configuration assignment of peptidomimetics with a terminal chiral 3-arylpropionic acid unit
Frelek, Jadwiga,Fryszkowska, Anna,Kwit, Marcin,Ostaszewski, Ryszard
, p. 2469 - 2478 (2007/10/03)
The relationship between the molecular structure of peptidomimetics 1 and their chiroptical properties has been studied using circular dichroism spectroscopy. It was demonstrated that the sign of the Cotton effects occurring around 230 and 270 nm enables the direct assignment of stereochemistry at C-1 and C-3 carbon atoms. The TD-DFT calculations of the circular dichroism (CD) spectrum of one of the model compounds confirm the absolute stereochemistry assignment made experimentally. Thus, CD spectroscopy proved to be a simple, reliable and general tool for the determination of the absolute configuration of the stereogenic centers of peptidomimetics with a terminal 3-arylpropionic group.
Synthesis and Circular Dichroism Spectra of Sperm Whale Myoglobin-(57-96)-Tetracontapeptide
Hashimoto, Chikao,Muramatsu, Ichiro
, p. 181 - 190 (2007/10/02)
A protected sperm whale myoglobin-(57-96)-tetracontapeptide (29) was synthesized by successive condensations of three fragments, Boc-(70-76)-OH, Boc-(62-69)-OH, and Boc-(57-61)-OH to a partially protected eicosapeptide ester, H-(77-96)-OBzl.After removal
SYNTHESIS OF A DECAPEPTIDE WITH THE SEQUENCE 1-10 OF HUMAN CALCITONIN WITH MINIMUM PROTECTION OF THE AMINO ACIDS
Zel'tser, I. E.,Tikhomirova, S. P.,Krysin, E. P.,Smirnov, M. B.
, p. 356 - 361 (2007/10/02)
A decapeptide with sequence 1-10 of human calcitonin has been synthesized by a 5 + 5 scheme with the minimum protection of the side-chain functional groups of the amino acid.
Synthesis and Carbon 13 N.M.R. Spectrum of the Peptide Fragment of Myelin Basic Protein (Human)
Pasaribu, Stephanus J.
, p. 2427 - 2440 (2007/10/02)
The tridecapeptide Phe-Lys-Leu-Gly-Gly-Arg-Asp-Ser-Arg-Ser-Gly-Ser-Pro-OH, and its methyl ester derivative at the carbonyl terminal, -Pro-OMe, were synthesized by the solution phase method.The synthesis was accomplished by fragment condensation of a tetra
