218449-32-2

Basic information

• Product Name: 2-aMino-2-(3,4-difluorophenyl)ethanol hydrochloride
• Synonyms: 2-aMino-2-(3,4-difluorophenyl)ethanol hydrochloride;2-AMINO-2-(3,4-DIFLUOROPHENYL)ETHAN-1-OL;2-Amino-2-(3,4-difluorophenyl)ethanol;2-(3,4-Difluorophenyl)-2-aminoethanol
• CAS NO: 218449-32-2
• Molecular Formula: C₈H₉F₂NO
• Molecular Weight: 209.6209064
• Mol File: 218449-32-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-aMino-2-(3,4-difluorophenyl)ethanol hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-aMino-2-(3,4-difluorophenyl)ethanol hydrochloride(218449-32-2)
• EPA Substance Registry System: 2-aMino-2-(3,4-difluorophenyl)ethanol hydrochloride(218449-32-2)

Safety Data

• Hazardous Substances Data: 218449-32-2(Hazardous Substances Data)

Usage

Usage

Pharmaceutical Intermediate: Commonly used in the synthesis of various drugs and pharmaceuticals.
Chiral Building Block: Utilized in the synthesis of pharmaceutical compounds due to its specific chemical structure.

Potential Applications

Medicinal Chemistry: Can be applied in medicinal chemistry for drug development.

Safety Precautions

Toxicity: Potential for toxicity necessitates careful handling.
Good Laboratory Practices: Must be handled in accordance with proper safety precautions and good laboratory practices to mitigate harmful effects.

Upstream product

• 218449-31-1 amino-(3,4-difluorophenyl)-acetic acid methyl ester 
• 60-29-7 diethyl ether 
• 225641-91-8 4-(3,4-difluorophenyl)-2-oxazolidinone 
• 34036-07-2 3,4 difluorobenzaldehyde 
• 218449-30-0 amino-(3,4-difluorophenyl)-acetonitrile 

Downstream Products

• 225641-91-8 4-(3,4-difluorophenyl)-2-oxazolidinone 
• 218449-37-7 4-(3,4-difluorophenyl)-2-oxo-oxazolidine-3-carboxylic acid-4-nitro-phenyl ester 
• 218451-40-2 (+)-3-(3-(4-Aminocarbonyl-4-(4-chloro)phenylpiperidin-1-yl)-propyl)aminocarbonyl-4-(3,4-difluoro)phenyl-2-oxazolidinone 
• 218451-28-6 (+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone 
• 1609164-81-9 rac-8-[(2,6-difluorobenzyl)oxy]-N-[1-(3,4-difluorophenyl)-2-hydroxyethyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide 
• 218449-35-5 [1-(3,4-difluorophenyl)-2-hydroxy-ethyl]-carbamic acid-tert-butyl ester 

Relevant articles and documents

BENZOPYRAZOLE COMPOUND USED AS RHO KINASE INHIBITOR

The invention relates to a benzopyrazole compound used as RHO kinase inhibitor, a pharmaceutical composition and uses thereof for preparing an RHO kinase inhibiting drug, and more specifically to said compound of formula (I-1), a pharmaceutically acceptable salt and isomer thereof.

MORPHOLINONE AND MORPHOLINE DERIVATIVES AND USES THEREOF

This invention is directed to morpholinone and morpholine derivatives which are selective antagonists for human α 1a receptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of benign prostatic hyperplasia, impotency, cardiac arrhythmia, sympathetic mediated pain, migraine, and for the treatment of any disease where the antagonism of the α 1a receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.