21848-95-3

Upstream product

• 2769-64-4 n-butyl isonitrile 
• 622-37-7 Phenyl azide 
• 62-53-3 aniline 
• 103-72-0 phenyl isothiocyanate 
• 6336-01-2 3-n-butyl-1-phenylthiourea 
• 3083-88-3 N-butyl-N'-phenylurea 

Downstream Products

• 127704-13-6 3-phenyl-1,3-oxazin-2-(N-n-butyl)imine 
• 121518-17-0 Butyl-[4-methyl-3-phenyl-oxazolidin-(2Z)-ylidene]-amine 
• 101835-26-1 Butyl-[5-methyl-3-phenyl-oxazolidin-(2Z)-ylidene]-amine 
• 101835-26-1 N-butyl-3-phenyl-5-methyl-1,3-oxazolidin-2-imine 
• 132783-02-9 Butyl-[(4R,5S)-4,5-dimethyl-3-phenyl-oxazolidin-(2Z)-ylidene]-amine 
• 132783-02-9 Butyl-[(4R,5R)-4,5-dimethyl-3-phenyl-oxazolidin-(2Z)-ylidene]-amine 
• 10204-16-7 2-(butylamino)-3-phenylquinazolin-4(3H)-one 
• 1284224-18-5 N-butyl-1-phenyl-1H-2-aminobenzimidazole 
• 85285-38-7 N-butyl-1-phenyl-1H-tetrazol-5-amine 
• 101306-22-3 C₁₂H₁₇N₃O₂ 
• 121485-60-7 Butyl-[5-methoxymethyl-3-phenyl-oxazolidin-(2Z)-ylidene]-amine 
• 121485-55-0 Butyl-[4-methoxymethyl-3-phenyl-oxazolidin-(2Z)-ylidene]-amine 
• 137146-08-8 2-butylimino-5-ethyl-3-phenyl-1,3-oxazolidine 
• 137146-04-4 2-butylimino-4-ethyl-3-phenyl-1,3-oxazolidine 

Relevant academic research and scientific papers

Palladium-catalyzed cross-coupling reaction of azides with isocyanides

An efficient palladium-catalyzed cross-coupling reaction of azides with isocyanides is developed, providing a general synthetic route to unsymmetric carbodiimides with excellent yields. This method shows a broad substrate scope, including not only aryl azides, but also unactivated benzyl and alkyl azides. Furthermore, from readily available substrates, Pd-catalyzed coupling with a tandem amine insertion cascade to obtain unsymmetric trisubstituted guanidines has been achieved in a one-pot fashion.

A versatile thiouronium-based solid-phase synthesis of 1,3,5-triazines

A thiouronium-based solidphase synthesis of a 1,3,5-triazine scaffold has been developed. The key feature of the synthesis is the use of a readily accessible solid-supported thiouronium salt as a primary precursor for the stepwise assembly of the 1,3,5-tri-azine substrate. The sulfur linker employed in the synthesis is stable under both acidic and basic conditions and is versatile enough to provide access to monocyclic, bicyclic, and spirocyclic compounds with the 1,3,5-triazine scaffold. By using this synthetic strategy, a representative set of 79 compounds containing the 1,3,5-triazine scaffold were prepared.

Highly Enantioselective Synthesis of 1,3-Oxazolidin-2-imine Derivatives by Asymmetric Cycloaddition Reactions of Vinyloxiranes with Unsymmetrical Carbodiimides Catalyzed by Palladium(0) Complexes

4-Vinyl-1,3-oxazoilidin-2-imine derivatives have been synthesized by cycloaddition reactions of 2-vinyloxiranes with unsymmetrical carbodiimides catalyzed by palladium(0) complexes in excellent total isolated yields. After reaction two compounds were alwa

DI-2-PYRIDYL THIONOCARBONATE. A NEW REAGENT FOR THE PREPARATION OF ISOTHIOCYANATES AND CARBODIIMIDES.

Reaction of amines with di-2-pyridyl thionocarbonate affords the corresponding isothiocyanates at room temperature, while reaction of N,N'-disubstituted thioureas with di-2-pyridyl thionocarbonate in the presence of 4-dimethylaminopyridine as a catalyst affords the corresponding carbodiimides in high yields.