218629-47-1Relevant academic research and scientific papers
Improved difluorination of cyclohexenones using morph-DAST by the application of ultra-high pressure
Box, Julian M.,Harwood, Laurence M.,Whitehead, Roger C.
, p. 571 - 573 (2007/10/03)
2,6- and 6,6- difluorinated α-substituted cyclohexenes have been prepared by the action of morpholinosulfur trifluoride on the corresponding cyclohex-2-enones under thermal conditions. The overall efficiency of this process has been significantly improved by the application of ultra high pressure (10-19Kbar). Investigations into the scope of this methodology have resulted in the preparation of the novel fluorinated compounds: 6,6-difluorolimonene and 3,3-difluoro-4-cholestene.
