218767-33-0Relevant academic research and scientific papers
Studies on the biomimetic synthesis of the manzamine alkaloids
Baldwin,Claridge,Culshaw,Heupel,Lee,Spring,Whitehead
, p. 3154 - 3161 (2007/10/03)
The biomimetic synthesis of the manzamine-related alkaloid keramaphidin B is described. The key intramolecular Diels-Alder reaction proposed in the Baldwin and Whitehead hypothesis is demonstrated. An investigation of the modified biomimetic hypothesis pr
Investigations into the manzamine alkaloid biosynthetic hypothesis
Baldwin, Jack E.,Claridge, Timothy D. W.,Culshaw, Andrew J.,Heupel, Florian A.,Lee, Victor,Spring, David R.,Whitehead, Roger C.,Boughtflower, Robert J.,Mutton, Ian M.,Upton, Richard J.
, p. 2661 - 2663 (2007/10/03)
The biomimetic synthesis of a pentacyclic alkaloid (keramaphidin B, 1), an intermediate in the biogenetic pathway to the manzamine alkaloids, has been achieved. Compound 1 was formed by an intramolecular Diels-Alder reaction of macrocycle 2 in buffer foll
