21882-31-5 Usage
Uses
Used in Pharmaceutical Industry:
2,4-diamino-N,N-diethylquinazoline-6-sulfonamide is used as a potential active pharmaceutical ingredient for [application reason], leveraging its sulfonamide and quinazoline structures which are known for their antibacterial and pharmacological properties, respectively.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2,4-diamino-N,N-diethylquinazoline-6-sulfonamide is used as a compound of interest for [application reason], due to its unique structural features that may contribute to the development of new drugs with specific therapeutic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 21882-31-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,8,8 and 2 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 21882-31:
(7*2)+(6*1)+(5*8)+(4*8)+(3*2)+(2*3)+(1*1)=105
105 % 10 = 5
So 21882-31-5 is a valid CAS Registry Number.
21882-31-5Relevant academic research and scientific papers
Folate antagonists. 22. Antimalarial and antibacterial effects of 2,4-diamino-6-quinazolinesulfonamides
Elslager,Colbry,Davoll,Hutt,Johnson,Werbel
, p. 1740 - 1743 (2007/10/02)
The synthesis and antimalarial activity of a series of 2,4-diamino-6-quinazolinesulfonamides is described. Chlorosulfonation of 2,4-quinazolinediamine affords the 6-sulfonyl chloride, which upon treatment with the appropriate amine produces the desired products. Alternatively the sulfonyl chloride could be introduced by diazotization of the corresponding amine followed by treatment with SO2 in the presence of CuCl2. Although substantial antimalarial activity was demonstrated for several members of this class, studies were discontinued in light of the potency of related series.
