21888-99-3 Usage
Uses
Used in Pharmaceutical Research:
[3,4'-Bipiperidine]-2,6-dione,3-phenyl-1'-(phenylmethyl)-, (3R)is used as a research compound for its potential role in drug discovery and development. [3,4'-Bipiperidine]-2,6-dione,3-phenyl-1'-(phenylmethyl)-, (3R)-'s unique structure and stereochemistry make it a valuable candidate for studying interactions with biological targets, which could lead to the development of new therapeutic agents.
Used in Chemical Research:
In the field of chemical research, [3,4'-Bipiperidine]-2,6-dione,3-phenyl-1'-(phenylmethyl)-, (3R)is used as a starting material or intermediate for the synthesis of more complex molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Drug Design:
[3,4'-Bipiperidine]-2,6-dione,3-phenyl-1'-(phenylmethyl)-, (3R)is used as a structural template in drug design, where its specific stereochemistry and structural features can be exploited to create new molecules with desired pharmacological properties. This application aims to develop novel drugs with improved efficacy, selectivity, and safety profiles.
Used in Medicinal Chemistry:
In medicinal chemistry, [3,4'-Bipiperidine]-2,6-dione,3-phenyl-1'-(phenylmethyl)-, (3R)is used as a lead compound for optimizing the properties of potential drug candidates. Researchers can modify the structure of [3,4'-Bipiperidine]-2,6-dione,3-phenyl-1'-(phenylmethyl)-, (3R)- to enhance its biological activity, pharmacokinetics, and drug-like properties, ultimately aiming to develop more effective therapeutic agents.
Used in Drug Synthesis:
[3,4'-Bipiperidine]-2,6-dione,3-phenyl-1'-(phenylmethyl)-, (3R)is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structural features make it an attractive building block for the development of new drugs with diverse mechanisms of action and therapeutic applications.
Used in Drug Delivery Systems:
[3,4'-Bipiperidine]-2,6-dione,3-phenyl-1'-(phenylmethyl)-, (3R)may be used in the development of drug delivery systems, where its structural properties can be utilized to improve the bioavailability, targeting, and release of therapeutic agents. This application aims to enhance the overall efficacy and safety of drug treatments by ensuring that the active pharmaceutical ingredients are delivered to the desired site of action in the body.
Check Digit Verification of cas no
The CAS Registry Mumber 21888-99-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,8,8 and 8 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 21888-99:
(7*2)+(6*1)+(5*8)+(4*8)+(3*8)+(2*9)+(1*9)=143
143 % 10 = 3
So 21888-99-3 is a valid CAS Registry Number.
21888-99-3Relevant academic research and scientific papers
PIPERIDINE DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS
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Page/Page column 65, (2008/06/13)
The present invention relates to a compound of formula (I), aN-oxide thereof, a pharmaceutically acceptable salt thereof, a stereochemically isomeric form thereof or a solvate thereof, wherein X represents N or CH; Y and Z each independently represent C(=O) or CH2 provided that at least one of Y and Z represents C(=O); R1 represents CH(R4)-aryl or CH(R4)-heteroaryl; R2 represents aryl2 or heteroaryl; R3 represents hydrogen; C1-4alkylcarbonyl; C1-6alkyl optionally substituted with C1-6alkyloxy, C1-6alkylthio, C1-6alkyloxycarbonyl or aryl1 ; provided that when Y and Z each represent C(=O), X represents CH, R3 represents hydrogen, R4 represents hydrogen, and R2 represents unsubstituted pyridyl or phenyl optionally substituted with one halo or with one C1-4alkyloxy or with one or two C1-4alkyl, then aryl in the definition of R1 is other than phenyl substituted with one halo or with one or two C1-4alkyl; and provided that when Y and Z each represent C(=O), X represents CH, R3 represents hydrogen, and R2 represents unsubstituted pyridyl or phenyl optionally substituted with one halo or with one C1-4alkyloxy or with one or two C1-4alkyl, then heteroaryl in the definit ion of R1 is other than unsubstituted thienyl or unsubstituted pyridyl. The present invention also relates to the use of a compound of formula (I) for the manufacture of a medicament for preventing or treating a disease mediated through activation of the CXCR3 receptor; to processes for preparing the compounds of formula (I) and pharmaceutical compositions comprising them.
