21889-13-4

Usage

Uses

Used in Pharmaceutical Industry:
1,3-Indandione, 2-(4-dimethylaminophenylmethylene) is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Dye Industry:
1,3-Indandione, 2-(4-dimethylaminophenylmethylene) is used as a precursor in the production of dyes, contributing to the development of new colorants for various applications, such as textiles, plastics, and printing inks.
Used in Organic Chemicals Industry:
1,3-Indandione, 2-(4-dimethylaminophenylmethylene) is used as a reagent in the synthesis of various organic chemicals, enabling the creation of new compounds with diverse applications in different industries.
Used in Antioxidant and Anti-Inflammatory Applications:
1,3-Indandione, 2-(4-dimethylaminophenylmethylene) is being investigated for its potential antioxidant and anti-inflammatory properties, which could lead to its use in the development of new treatments for various diseases and disorders.
Used in Disease and Disorder Treatment Research:
1,3-Indandione, 2-(4-dimethylaminophenylmethylene) is being studied for its potential use in the treatment of various diseases and disorders, making it a promising candidate for further research and development in the pharmaceutical field.

InChI:InChI=1/C18H15NO2/c1-19(2)13-9-7-12(8-10-13)11-16-17(20)14-5-3-4-6-15(14)18(16)21/h3-11H,1-2H3

Upstream product

• 606-23-5 1H-indene-1,3(2H)-dione 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 889-37-2 N,N-dimethyl-4-((phenylimino)methyl)aniline 
• 84-66-2 Diethyl phthalate 

Downstream Products

• 49764-75-2 (4-N,N-dimethylaminophenyl)(1,3-dioxo-2-indanylidene)acetonitrile 
• 967-04-4 2-(4-dimethylamino-benzyl)-indan-1,3-dione 
• 88874-07-1 3'-(4-Dimethylaminophenyl)-1,3-dioxo-indan-2-spiro-2'-oxiran 
• 2471-89-8 2-[1-(4-Dimethylamino-phenyl)-2-nitro-ethyl]-indan-1,3-dione 
• 1259377-22-4 4-(2-(4-(dimethylamino)phenyl)-1',3'-dioxo-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-3-yl)benzonitrile 
• 1057717-27-7 C₃₂H₂₅N₂O₄S^(1-)*K⁽¹⁺⁾ 
• 1093169-03-9 4-(1-cyano-2-(4-(dimethylamino)phenyl)-2-(1,3-dioxo-2,3-dihydro-1H-inden-2-yl)ethyl)-benzonitrile 

Relevant academic research and scientific papers

T-shaped D?π?A?(π?A)2 chromophores with two auxiliary electron acceptors

A series of tripodal push-pull chromophores based on central indan-1,3-dione scaffold has been designed and synthesized by Knoevenagel condensation and Pd-catalyzed Suzuki-Miyaura cross-coupling reaction. Target molecules possess D?π?A?(π?A)2 e

Blue-to-red light sensitive push-pull structured photoinitiators: Indanedione derivatives for radical and cationic photopolymerization reactions

The actual photonitiators PI can only operate in a restricted part of the visible spectrum; as a consequence, several PIs are usually necessary to harvest all the emitted visible photons. In the present paper, new dyes based on a donor-π-acceptor structur

Selected drug-likeness properties of 2-arylidene-indan-1,3-dione derivatives—chemical compounds with potential anti-cancer activity

2-Arylidene-indan-1,3-done derivatives have very different properties, thanks to which they find various applications in science, medicine, and industry. Selected derivatives show antivi-ral, antibacterial, and anti-inflammatory activity. This paper prese

Leishmanicidal and cytotoxic activities and 4D-QSAR of 2-arylidene indan-1,3-diones

The indan-1,3-dione and its derivatives are important building blocks in organic synthesis and present important biological activities. Herein, the leishmanicidal and cytotoxicity evaluation of 16 2-arylidene indan-1,3-diones is described. The compounds w

Zirconium catalyzed synthesis of 2-arylidene Indan-1,3-diones and evaluation of their inhibitory activity against NS2B-NS3 WNV protease

A simple and efficient Knoevenagel procedure for the synthesis of 2-arylidene indan-1,3-diones is herein reported. These compounds were prepared via ZrOCl2·8H2O catalyzed reactions of indan-1,3-dione with several aromatic aldehydes and using water as the

Benzylidine indane-1,3-diones: As novel urease inhibitors; synthesis, in vitro, and in silico studies

Current study deals with the evaluation of indane-1,3-dione based compounds as new class of urease inhibitors. For that purpose, benzylidine indane-1,3-diones (1–30) were synthesized and fully characterized by different spectroscopic techniques including

Biocompatible Fluorescence Nanoparticles and Uses Thereof

The present invention relates to a novel bipolar aryl vinyl compound, nano-probe particles including the same, a contrast agent using the same, and an imaging method thereof. The novel bipolar aryl vinyl compound can adjust the solid-state fluorescence (S

Microwave-promoted, catalyst-free, multi-component reaction of proline, aldehyde, 1,3-diketone: One pot synthesis of pyrrolizidines and pyrrolizinones

One-pot, three-component preparation of the pyrrolizidine and pyrrolizinone derivatives in moderate to good yield is reported. The synthesis is facilitated by microwave irradiation of proline, aromatic aldehyde, and 1,3-diketone such as 2-arylmethylene-in

Characterization of the Fluorescence Properties of 4-Dialkylaminochalcones and Investigation of the Cytotoxic Mechanism of Chalcones

Understanding the mechanisms responsible for the various biological activities of chalcones, particularly the direct cellular targets, presents an unmet challenge. Here, we prepared a series of fluorescent chalcone derivatives as chemical probes for their

Aqueous extract of Balanites roxburghii fruit: A green dispersant for C-C bond formation

An aqueous biosurfactant solution, a biobased green acidic catalyst for Knoevenagel condensation of 1,3-indanedione with aryl aldehydes and tandem Knoevenagel-Michael reaction of 3-methyl-1-phenylpyrazole with aryl aldehydes, has been reported for the fir