218898-44-3Relevant academic research and scientific papers
Enantioselective synthesis of the C1-C11 fragment of bafilomycin A1 using non-wittig and desymmetrization strategies
Poupon, Jean-Christophe,Demont, Emmanuel,Prunet, Joelle,Ferezou, Jean-Pierre
, p. 4700 - 4707 (2007/10/03)
The synthesis of the C1-C11 fragment 33 of bafilomycin A1 was achieved. Intermediate ketone 16 was prepared in six steps from 4-oxopimelate 13. Desymmetrization of this ketone using Koga's chiral base followed by TMSCl quench furnished silyl en
