218938-79-5Relevant academic research and scientific papers
Regio- and diastereoselective SN2′ or SN2″ reactions on chiral acetals of cyclic aldehydes promoted by PhCu, BF3
Maze, Frederique,Purpura, Martin,Bernaud, Frederic,Mangeney, Pierre,Alexakis, Alexandre
, p. 1957 - 1960 (2007/10/03)
The regio- and diastereoselectivity of the addition of PhCu, BF3 reagent on chiral acetals derived from several mono or dienic aldehydes was studied. It was found that monoethylenic acetals react regio- and diastereoselectively via an overall a
Design, synthesis, and application of a C2 symmetric chiral ligand for enantioselective conjugate addition of organolithium to α,β-unsaturated aldimine
Shindo, Mitsuru,Koga, Kenji,Tomioka, Kiyoshi
, p. 9351 - 9357 (2007/10/03)
A C2 symmetric chiral diether ligand, (1R,2R)-1,2-dimethoxy-1,2- diphenylethane, was designed and synthesized on the basis of the concept of an asymmetric oxygen atom. Mediated by the chiral diether, high enantioselectivities were achieved in conjugate addition of organolithiums to naphthaldehyde imine and cyclic and acyclic α,β-unsaturated aldimines. The absolute configuration of the product is predictable by the model.
AUXILIARY-DIRECTED DIOXYGENATION: STEREOSELECTIVE SYNTHESIS OF A DIENE HYDROPEROXIDE
Dussault, Patrick H.,Hayden, Michael R.
, p. 443 - 446 (2007/10/02)
The presence of a chiral auxiliary is shown to induce highly stereoselective peroxidation of a tethered 1,4-diene.
