218947-50-3Relevant academic research and scientific papers
ACETYLENIC ALPHA-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS
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Page 50, (2010/02/07)
Compound of the formula (B) are useful in treating disease conditions mediated by TNF- alpha , such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
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, (2008/06/13)
Compounds of the formula: are useful in treating disease conditions mediated by TNF-α, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
The synthesis and biological activity of a novel series of diazepine MMP inhibitors
Levin, Jeremy I.,DiJoseph, John F.,Killar, Loran M.,Sung, Amy,Walter, Thomas,Sharr, Michele A.,Roth, Catherine E.,Skotnicki, Jerauld S.,Albright, J. Donald
, p. 2657 - 2662 (2007/10/03)
A novel series of diazepine-based hydroxamic acid inhibitors of MMP-1, MMP-9, and MMP-13 were prepared and evaluated both in vitro and in vivo.
