21895-10-3Relevant academic research and scientific papers
Manganese-Catalyzed Stereospecific Hydroxymethylation of Alkyl Tosylates
Shenouda, Hannah,Alexanian, Erik J.
, p. 9268 - 9271 (2019)
The development of a stereospecific hydroxymethylation of alkyl tosylates using an inexpensive, first-row catalyst is described. The transformation proceeds under mild conditions with low pressure to deliver homologated alcohols as products. Chiral, nonracemic β-branched primary alcohols are obtained with high enantiospecificity from easily accessed secondary alkyl substrates. Simple modification of the reaction system also permits access to α-d2 alcohols. These studies use anionic metal carbonyl catalysis to access a synthetic equivalent of the challenging hydroxymethyl anion from carbon monoxide.
Collision-induced Dissociations of Aryl-substituted Alkoxide Ions. Losses of Dihydrogen and Rearrangement Processes
Raftery, Mark J.,Bowie, John H.,Sheldon, John C.
, p. 563 - 570 (2007/10/02)
The ion PhCH2O- undergoes competitive losses of H., H2, CH2O, and C6H6 upon collisional activation.The loss of H2 occurs mainly to form (C6H4)-CHO, and ab initio calculations suggest the reaction proceeds by the stepwise m
