218956-26-4Relevant articles and documents
First synthesis of the antimalarial naphthylisoquinoline alkaloid dioncophylline C, and its unnatural anti-HIV dimer, jozimine C1
Bringmann, Gerhard,Holenz, Joerg,Weirich, Ralf,Ruebenacker, Martin,Funke, Christian,Boyd, Michael R.,Gulakowski, Robert J.,Francois, Guido
, p. 497 - 512 (2007/10/03)
The first total synthesis of dioncophylline C, a new antimalarial lead structure, is described. For the directed construction of the stereogenic biaryl axis, the 'lactone methodology' is applied, despite the lack of a 'bridgehead oxygen' function in the t