21900-55-0

Basic information

• Product Name: Benzoyl chloride, 4-bromo-2-chloro-
• CAS NO: 21900-55-0
• Molecular Formula: C7H3BrCl2O
• Molecular Weight: 253.91
• Mol File: 21900-55-0.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: Benzoyl chloride, 4-bromo-2-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 4-bromo-2-chloro-(21900-55-0)
• EPA Substance Registry System: Benzoyl chloride, 4-bromo-2-chloro-(21900-55-0)

Safety Data

• Hazardous Substances Data: 21900-55-0(Hazardous Substances Data)

Upstream product

• 79-37-8 oxalyl dichloride 
• 59748-90-2 4-Bromo-2-chloro-benzoic Acid 
• 119-32-4 4-Methyl-3-nitroanilin 
• 89794-02-5 4-bromo-2-chlorotoluene 

Downstream Products

• 131994-22-4 ethyl 3-(4-bromo-2-chlorophenyl)-3-oxo-propionate 
• 119878-34-1 4-Bromo-2-chloro-N-methyl-N-((5S,6R)-1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide 
• 682778-17-2 N,N-diethyl-4-bromo-2-chlorobenzamide 
• 850035-47-1 N,N-diethyl-2-chloro-4-ethylbenzamide 
• 850035-46-0 N,N-diethyl-2-chloro-4-ethenylbenzamide 
• 131994-23-5 (Z)-2-(4-Bromo-2-chloro-benzoyl)-3-dimethylamino-acrylic acid ethyl ester 
• 131994-49-5 7-Bromo-1-(4-fluoro-phenyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 
• 131994-50-8 7-Bromo-1-(4-fluoro-phenyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid amide 
• 131994-20-2 ethyl 7-bromo-1,4-dihydro-1-(4-fluorophenyl)-4-oxo-3-quinolinecarboxylate 
• 131994-26-8 ethyl 7-ethynyl-1,4-dihydro-1-(4-fluorophenyl)-4-oxo-3-quinolinecarboxylate 
• 131994-28-0 1,4-Dihydro-1-(4-fluorophenyl)-7-(3-methyl-5-isoxazolyl)-4-oxo-3-quinolinecarboxylic acid 
• 131994-24-6 ethyl 1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-<(trimethylsilyl)ethynyl>-3-quinolinecarboxylate 
• 131994-27-9 ethyl 1-(4-fluorophenyl)-1,4-dihydro-7-<5-(3-methylisoxazolyl)>-4-oxo-3-quinolinecarboxylate 
• 220461-97-2 (4-bromo-2-chloro-phenyl)-(5H,11H-pyrrolo[2,1-c][1,4]benzodiazepin-10-yl)-methanone 

Relevant articles and documents

Synthesis and SAR studies of novel benzodiazepinedione-based inhibitors of Clostridium difficile (C. difficile) toxin B (TcdB)

Synthesis and structure-activity relationships (SAR) of a novel series of benzodiazepinedione-based inhibitors of Clostridium difficile toxin B (TcdB) are described. Compounds demonstrating low nanomolar affinity for TcdB, and which possess improved stability in mouse plasma vs. earlier compounds from this series, have been identified. Optimized compound 11d demonstrates a good pharmacokinetic (PK) profile in mouse and hamster and is efficacious in a hamster survival model of Clostridium difficile infection.

NOVEL 3,5-DISUBSTITUTED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUTED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF C-MET PROTEIN, ETC

The present invention provides compounds useful as c-Met protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of c-Met kinase mediated disease or disorders with them.

2- PYRIDONE COMPOUND

PROBLEM TO BE SOLVED: To provide a compound that has excellent glucokinase (GK) activating action and is useful as a pharmaceutical. SOLUTION: The present invention provides a 2-pyridone compound represented by formula [1], and a tautomer or stereoisomer of the compound, or their pharmacologically acceptable salts, or their solvates (where R1 is RA-ZA-; RA is any of a carboxy group, a sulfo group or formula [5]). COPYRIGHT: (C)2016,JPOandINPIT