21901-43-9Relevant academic research and scientific papers
Continuous flow nucleophilic aromatic substitution with dimethylamine generated in situ by decomposition of DMF
Petersen, Trine P.,Larsen, Anders Foller,Ritzen, Andreas,Ulven, Trond
, p. 4190 - 4195 (2013/05/23)
A safe, practical, and scalable continuous flow protocol for the in situ generation of dimethylamine from DMF followed by nucleophilic aromatic substitution of a broad range of aromatic and heteroaromatic halides is reported.
HETEROARYL- SUBSTITUTED PYRROLO` 2, 3- B! PYRIDINE DERIVATIVES AS CRF RECEPTOR ANTAGONISTS
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Page/Page column 36, (2010/02/07)
The present invention provides compounds of formula (I) including stereoisomers, prodrugs and pharmaceutically acceptable salts or solvates thereof, to processes for their preparation, to pharmaceutical compositions containing them and to their use in the treatment of conditions mediated by corticotropin-releasing factor (CRF).
