21902-96-5

Usage

Uses

Used in Pharmaceutical Industry:
(22R)-5β,6β-Epoxy-3-methoxy-1-oxo-4β,22,27-trihydroxyergost-24-en-26-oic acid 26,22-lactone is used as a bioactive molecule for its potential anti-inflammatory, antifungal, and antiproliferative effects. Its unique structure allows it to be a promising candidate in the development of new drugs for various medical applications.
Further research is necessary to fully understand the biological activities and potential uses of (22R)-5β,6β-Epoxy-3-methoxy-1-oxo-4β,22,27-trihydroxyergost-24-en-26-oic acid 26,22-lactone, as it may lead to the creation of novel therapeutic agents.

Upstream product

• 674-26-0 mevalonolactone 
• 67-56-1 methanol 
• 5119-48-2 withaferin-A 

Relevant academic research and scientific papers

BIOSYNTHESIS OF WITHANOLIDES IN ACNISTUS BREVIFLORUS

Acnistus breviflorus; Solanaceae; withaferin A; withanolide; biosynthesis.Administration of mevalonolactone to excised leaves of Acnistus breviflorus produced labelled withaferin A and jaborosalactone A.The former was degraded leading to the isolation of glyceric acid from C-25-C-27 of the withanolide.These carbons represented only 2percent of the total radioactivity of withaferin A.The relative radioactivity of these carbons indicated that C-26 is directly derived from C-2 of mevalonolactone suggesting that the 25-pro-R-methyl group of cholesterol or any other sterol intermediate had been oxidized to form the lactone ring of the withanolide.The total radioactivity value found for C-25-C27 was much lower than the expected 20percent of the total value for the withanolide indicating that the side chain of the sterol precursor had been partially cleaved during the biosynthetic process.