219123-72-5

Upstream product

• 219123-67-8 (R)-5-[(1R,3aR,4S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-2-oxo-hexanoic acid methyl ester 
• 100928-04-9 (S)-2-((1R,3aR,4S,7aR)-4-((tert-butyldimethylsilyl)oxy)-7a-methyloctahydro-1H-inden-1-yl)propyl 4-methylbenzenesulfonate 
• 145223-29-6 (R)-3-((1R,3aR,4S,7aR)-4-((tert-butyldimethylsilyl)oxy)-7a-methyloctahydro-1H-inden-1-yl)butanenitrile 
• 50-14-6 Calciferol 
• 1519-39-7 (R)-methyl p-tolyl sulfoxide 
• 219123-69-0 (R)-5-[(1R,3aR,4S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-2,2-difluoro-hexanoic acid methyl ester 
• 64190-52-9 (8S,20S)-de-A,B-20-(hydroxymethyl)pregnan-8-ol 
• 66774-80-9 (S)-2-((3R,3aR,7S,7aR)-octahydro-7-hydroxy-3a-methyl-1H-inden-3-yl)propyl 4-methylbenzenesulfonate 
• 93489-71-5 (R)-3-((1R,3aR,4S,7aR)-4-((tert-butyldimethylsilyl)oxy)-7a-methyloctahydro-1H-inden-1-yl)butanal 

Downstream Products

• 219123-74-7 (2R,6R)-6-[(1R,3aR,4S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-3,3-difluoro-2-methyl-1-((R)-toluene-4-sulfinyl)-heptan-2-ol 

Relevant academic research and scientific papers

Stereoselective synthesis and structural establishment of (25S)-24,24- difluoro-1α,25,26-trihydroxyvitamin D3, a major metabolite of 24,24- difluoro-1α,25-dihydroxyvitamin D3

(25S)-24,24-Difluoro-1α,25,26-trihydroxyvitamin D3 (3a) and its (25R)- epimer (3b), either of which is expected to be a major metabolite of 24,24- difluoro-1α,25-dihydroxyvitamin D3 (2), were synthesized. Asymmetric addition to β-ket