219130-31-1

Basic information

• Product Name: 3-Pyridinecarboxamide, 6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-
• CAS NO: 219130-31-1
• Molecular Formula: C17H17F3N4O
• Molecular Weight: 350.343
• Mol File: 219130-31-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxamide, 6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxamide, 6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-(219130-31-1)
• EPA Substance Registry System: 3-Pyridinecarboxamide, 6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-(219130-31-1)

Safety Data

• Hazardous Substances Data: 219130-31-1(Hazardous Substances Data)

Upstream product

• 6271-78-9 6-chloro-3-pyridinecarboxamide 
• 15532-75-9 1-(3-Trifluoromethylphenyl)piperazine 

Downstream Products

• 219130-33-3 6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-3-pyridinecarbothioamide 

Relevant articles and documents

Synthesis and anti-angiogenic activity of 6-(1,2,4-thiadiazol-5-yl)-3-amino pyridazine derivatives

General screening for inhibitors of microvessel growth in vitro in the rat aortic ring assay led to the discovery of a novel series of thiadiazole pyridazine compounds with potential anti-angiogenic activity. Chemical optimization produced orally active compounds with potent in vitro and in vivo anti-angiogenesis and anti-tumor activities.