2192-06-5 Usage
General Description
2-AMINO-4,5-DIHYDRO-1,3-THIAZOL-4-ONE HYDROCHLORIDE, also known as thioacetazone hydrochloride, is a chemical compound with potential applications in the pharmaceutical industry. It is a derivative of thiosemicarbazide and has been investigated for its potential antimicrobial and antitubercular properties. Thioacetazone has been used in combination therapy for the treatment of tuberculosis, particularly in cases of drug-resistant strains. It is believed to work by inhibiting the growth of mycobacteria, the bacteria responsible for tuberculosis, though its precise mechanism of action is not fully understood. Thioacetazone hydrochloride is typically administered orally and is considered to have a favorable safety profile, with the most common side effects being gastrointestinal discomfort and skin rash.
Check Digit Verification of cas no
The CAS Registry Mumber 2192-06-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,9 and 2 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2192-06:
(6*2)+(5*1)+(4*9)+(3*2)+(2*0)+(1*6)=65
65 % 10 = 5
So 2192-06-5 is a valid CAS Registry Number.
InChI:InChI=1/C3H4N2OS.ClH/c4-3-5-2(6)1-7-3;/h1H2,(H2,4,5,6);1H
2192-06-5Relevant articles and documents
Synthesis and alkylation of hexahydro-1,3,5-triazine-2-thione derivatives
Lazarev,Ramsh,Ivanenko
, p. 442 - 449 (2007/10/03)
A series of new hexahydro-1,3,5-triazine-2-thione derivatives were prepared by aminomethylation of thiourea with formaldehyde and primary amines; with aniline as amine component, an abnormal aminomethylation product is formed, 5-phenyl-1-phenylaminomethylhexahydro-1,3,5-triazine-2-thione. Alkylation of 5-tert-butylhexahydro-1,3,5-triazine-2-thione with alkyl halides and with methyl and ethyl bromoacetate yields hydrohalides of 2-alkylthio- and 2-alkoxycarbonylmethylthio-5-tert-butyl-3,4,5,6-tetrahydro-1,3,5-triazines, respectively.
