21921-33-5

Usage

Uses

Used in Paints and Coatings Industry:
1-isopropyl-2-imidazolidinone (SALTDATA: FREE) is used as a solvent for its high solvency power and low volatility, enabling the production of high-quality paints and coatings with improved performance and durability.
Used in Adhesives Industry:
1-isopropyl-2-imidazolidinone (SALTDATA: FREE) is used as a solvent in the formulation of adhesives, providing strong bonding properties and enhancing the overall performance of the adhesive products.
Used in Cleaning Products Industry:
1-isopropyl-2-imidazolidinone (SALTDATA: FREE) is used as a solvent in cleaning products, offering effective cleaning capabilities while being a safer alternative to traditional solvents due to its low toxicity and low environmental impact.
Used in General Manufacturing Industry:
1-isopropyl-2-imidazolidinone (SALTDATA: FREE) is used as a versatile solvent in various manufacturing processes, providing effective dissolution of a wide range of materials while prioritizing safety and sustainability.

Upstream product

• 19522-67-9 N-isopropylethane-1,2-diamine 
• 57-13-6 urea 
• 124-38-9 carbon dioxide 

Downstream Products

• 1202923-33-8 3-benzyloxy-2-[5-(4-fluoro-benzyl)-thiazol-2-yl]-9-(3-isopropyl-2-oxo-imidazolidin-1-yl)-7-morpholin-4-yl-pyrido[1,2-a]pyrimidin-4-one 

Relevant academic research and scientific papers

1-ACRYLOYLIMIDAZOLIDINE-2-ONE COMPOUND

To provide a compound that is expected to be applied to cell culture materials, temperature-responsive polymer materials and the like.SOLUTION: The present invention relates to a 1-acryloylimidazolidine-2-one compound represented by formula (1) (where R1a is a hydrogen atom, a C1 to 4 alkyl group, a benzyl group or an oxyalkyl group represented by formula (2). R2a is a hydrogen atom or a C1 to 4 alkyl group. R3a is a hydrogen atom or a methyl group).SELECTED DRAWING: None

TYK2 INHIBITORS AND USES THEREOF

Described herein are compounds that are useful in treating a TYK2-mediated disorder. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, a proliferative disorder, an endocrine disorder, a neurological disorder, or a disorder associated with transplantation.

IMIDAZO [1,5-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted imidazo[1,5-a]pyrimidinyl carboxamide and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted imidazo[1,5-a]pyrimidinyl carboxamide compounds described herein include substituted 2-heterocyclyl-4-alkyl-imidazo[1,5-a]pyrirnidine-8-carboxamide compounds and variants thereof.

N-VINYLIMIDAZOLIDONE COMPOUND, AND POLYMER THEREOF

PROBLEM TO BE SOLVED: To provide an N-vinylimidazolidone compound polymer that is expected to be applied for a cell culture material, a temperature-responsive material and others. SOLUTION: The present invention provides a polymer polymerized with an N-vinylimidazolidone compound (1) as a monomer, or a copolymer comprising the monomer and a monomer of a different structure (R1 is H, C1-12 alkyl or acyl; R2 and R3 is H or methyl). SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS

The subject matter herein is directed to carbazole-containing amide, carbamate, and urea derivatives and pharmaceutically acceptable salts or hydrates thereof of structural formula I wherein the variable R1, R2, R3, R4, R5, R6, R7, A, D, E, G, J, L, M, Q, a, and b are accordingly described. Also provided are pharmaceutical compositions containing the compounds of formula I to treat a Cry-mediated disease or disorder, such as diabetes, complications associated with diabetes, Cushing's syndrome, NASH, NAFLD, asthma, and COPD.

IMIDAZOLIDINONES AND ANALOGS EXHIBITING ANTI-CANCER AND ANTI-PROLIFERATIVE ACTIVITIES

Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.

Highly efficient synthesis of cyclic ureas from CO2 and diamines by a pure CeO2 catalyst using a 2-propanol solvent

Pure cerium oxide (CeO2) acts as an effective and reusable heterogeneous catalyst for direct synthesis of cyclic ureas from CO2 and diamines even at a low CO2 pressure of 0.3 MPa. 2-Propanol is the most preferable solvent to provide good selectivity. The system composed of a CeO2 catalyst and a 2-propanol solvent is applied to various diamines to provide the corresponding cyclic ureas in high yields (78-98%), including six-membered-ring ureas that are difficult to be synthesized from CO 2. Based on the kinetic studies on the effect of CO2 pressure and amine concentration and FTIR studies on adsorption of ethylenediamine and CO2 onto CeO2, the following mechanism for the synthesis of cyclic urea is proposed: (1) formation of carbamic acid and carbamate species on CeO2, (2) decomposition of carbamic acid to a free amino group and CO2, (3) nucleophilic attack of the amino group on the carbamate on CeO2 to produce the cyclic urea and (4) desorption of the product and regeneration of CeO2.

Imidazolidone polyetheramine strength enhancing additives of epoxy resin systems

This invention discloses the composition and preparation of imidazolidone modified polyetheramines. The alkyl polyetheramine is derived from 2-isopropylaminoethylamine and urea. N-isopropyl-2-imidazolidone is the intermediate product, which is alkoxylated and aminated to prepare the N-isopropyl imidazolidone polyetheramine. This invention also discloses the composition and preparation of oxazolidinone modified polyetheramines by reductive amination of polyols derived from 4-ethyl-4-hydroxymethyl-2-oxazolidone. The products of this invention have been tested in epoxy resin applications and improved properties have been demonstrated. These products may also be useful in polyurea applications.