21926-61-4Relevant academic research and scientific papers
Baker's yeast catalyzed one-pot synthesis of bioactive 2-[benzylidene(or pyrazol-4-ylmethylene)hydrazono]-1,3-thiazolidin-4-one-5-yl-acetic acids
Chavan, Anusaya S.,Kharat, Arun S.,Bhosle, Manisha R.,Mane, Ramrao A.
, p. 103 - 107 (2018)
An efficient and simple one-pot protocol has been developed for synthesis of substituted derivatives of 2-hydrazono-4-thiazolidinone-5-acetic acids 4a-j and 6a-g by cyclocondensation of aryl/pyrazolyl aldehyde, thiosemicarbazide and maleic anhydride in acetonitrile in the presence of readily available whole cell biocatalyst, baker's yeast (Saccharomyces cerevisiae). The reaction is enhanced by ultrasonication.
