219316-43-5Relevant articles and documents
Structure-based design and synthesis of small molecule protein-tyrosine phosphatase 1B inhibitors
Yao, Zhu-Jun,Ye, Bin,Wu, Xiong-Wu,Wang, Shaomeng,Wu, Li,Zhang, Zhong-Yin,Burke Jr., Terrence R.
, p. 1799 - 1810 (2007/10/03)
Protein-tyrosine phosphatase (PTP) inhibitors are attractive as potential signal transduction-directed therapeutics which may be useful in the treatment of a variety of diseases. We have previously reported the X-ray structure of 1,1-difluoro-1-(2-naphtha