21943-45-3

Upstream product

• 14003-34-0 3-methyl-2-oxo-1,2-dihydroquinoxaline 
• 66003-76-7 Diphenyliodonium triflate 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 3240-34-4 [bis(acetoxy)iodo]benzene 

Downstream Products

• 112849-50-0 2a-Methyl-4-phenyl-1-pyridin-4-yl-2,2a-dihydro-1H,4H-azeto[1,2-a]quinoxalin-3-one 
• 112828-50-9 2a-Methyl-1,1,4-triphenyl-2,2a-dihydro-1H,4H-azeto[1,2-a]quinoxalin-3-one 
• 88392-71-6 (1S,2aR)-1,2a-Dimethyl-3-oxo-4-phenyl-2,2a,3,4-tetrahydro-1H-azeto[1,2-a]quinoxaline-1-carboxylic acid methyl ester 
• 88392-70-5 (1R,2aR)-1,2a-Dimethyl-3-oxo-4-phenyl-2,2a,3,4-tetrahydro-1H-azeto[1,2-a]quinoxaline-1-carboxylic acid methyl ester 
• 88392-69-2 (1S,2aR)-1,2a-Dimethyl-3-oxo-4-phenyl-2,2a,3,4-tetrahydro-1H-azeto[1,2-a]quinoxaline-1-carbonitrile 

Relevant academic research and scientific papers

Alkylation of quinoxalin-2(1H)-ones using phosphonium ylides as alkylating reagents

A practical and efficient methodology for the construction of 3-alkylquinoxalinones through base promoted direct alkylation of quinoxalin-2(1H)-ones with phosphonium ylides as alkylating reagents under metal- and oxidant-free conditions was developed. Various 3-alkylquinoxalin-2(1H)-ones were easily obtained in good to excellent yields. Tentative mechanistic studies suggest that this reaction is likely to involve a nucleophilic addition-elimination process.

Preparation method of 3-methylquinoxaline-2(1H)-one compounds

The invention discloses a preparation method of 3-methylquinoxaline-2(1H)-one compounds. The preparation method comprises the step of performing a visible light catalytic reaction on a quinoxaline ketone compound and iodobenzene diacetate under the action

Visible-light induced decarboxylative alkylation of quinoxalin-2(1H)-ones at the C3-position

A simple and efficient method for the visible light induced direct carbon alkylation of quinoxalin-2(1H)-ones at the C3 position is described. This protocol employs cheap and readily available phenyliodine(iii) dicarboxylates as the alkylation reagents to conduct decarboxylative radical coupling reaction with quinoxalin-2(1H)-ones. The process exhibits excellent compatibility to functional groups and provides a convenient and selective access to various 3-alkylquinoxalin-2(1H)-ones in good yields.

Metal-free regioselective formation of C-N and C-O bonds with the utilization of diaryliodonium salts in water: Facile synthesis of: N-Arylquinolones and aryloxyquinolines

Regioselective construction of crucial C-N and C-O bonds leading to N-Arylquinolones and aryloxyquinolines has been accomplished by employing easily accessible diaryliodonium salts and quinolones in water under metal-and ligand-free conditions. This opera