21947-33-1

Upstream product

• 100-02-7 4-nitro-phenol 
• 21947-32-0 Boc-L-Nle-OH·DCHA 

Downstream Products

• 65864-24-6 Boc-Nle-Asp(OBzl)-Phe-NH₂ 
• 107327-18-4 (S)-3-{(S)-2-[(S)-2-{[(3S,6S,9S,17R)-9-tert-Butoxycarbonylamino-3-butyl-2,5,8,11-tetraoxo-6-(4-sulfooxy-benzyl)-1,4,7,12-tetraaza-cycloheptadecane-17-carbonyl]-amino}-3-(1H-indol-3-yl)-propionylamino]-hexanoylamino}-succinamic acid 
• 107326-94-3 Boc-Tyr-Nle-D-Lys(Z)-Trp-Nle-Asp-NH₂ 
• 107326-90-9 (S)-3-{(S)-2-[(S)-2-{[(3S,6S,9S,17R)-9-tert-Butoxycarbonylamino-3-butyl-6-(4-hydroxy-benzyl)-2,5,8,11-tetraoxo-1,4,7,12-tetraaza-cycloheptadecane-17-carbonyl]-amino}-3-(1H-indol-3-yl)-propionylamino]-hexanoylamino}-succinamic acid 
• 107327-09-3 (S)-3-{(S)-2-[(S)-2-((R)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-hexanoylamino}-6-benzyloxycarbonylamino-hexanoylamino)-3-(1H-indol-3-yl)-propionylamino]-hexanoylamino}-succinamic acid; compound with trifluoro-acetic acid 
• 94236-49-4 Boc-L-Nle-L-Asp(Bzl)-NH₂ 

Relevant academic research and scientific papers

SULFOXONIUM YLIDE DERIVATIVES AS PROBES FOR CYSTEINE PROTEASE

The present invention relates to compounds of formula I bearing a sulfoxonium ylide moiety as warhead, or salts thereof. Such compounds can be used as activity-based probes for cysteine proteases such as cathepsin X, in methods of detecting cysteine protease activity and in related diagnostic or therapeutic methods.