21947-97-7

Usage

Uses

Used in Biochemistry Research:
BOC-CYS(DPM)-OH is employed as a protected amino acid in biochemistry research, facilitating the synthesis of complex polypeptides and proteins. Its protective groups ensure that the cysteine residue remains stable and unreactive until the desired point in the synthesis process.
Used in Peptide Synthesis:
In the field of peptide synthesis, BOC-CYS(DPM)-OH is used as a building block for creating larger polypeptide chains. The protection of the amino and sulfur groups by BOC and DPM, respectively, allows for controlled reactions and prevents unwanted side reactions during the synthesis process.
Used in Drug Manufacturing:
BOC-CYS(DPM)-OH is utilized in the pharmaceutical industry as a key component in the synthesis of therapeutic peptides and proteins. Its protective groups enable the production of drugs with specific amino acid sequences, which can be crucial for their biological activity and therapeutic efficacy.
Used in the Synthesis of Biologically Active Molecules:
BOC-CYS(DPM)-OH is used as a precursor in the synthesis of biologically active molecules, such as enzymes, hormones, and antibodies. The protection of the cysteine residue ensures that these molecules maintain their structural integrity and biological function throughout the synthesis process.

Upstream product

• 1070-19-5 N-(tert-butyloxycarbonyl) azide 
• 5191-80-0 S-diphenylmethyl-L-cysteine 
• 26988-51-2 Boc-Cys(Dpm)-OH*DCHA 
• 24424-99-5 di-tert-butyl dicarbonate 
• 10389-65-8 di-t-butoxycarbonyl-L-cystine 
• 776-74-9 Bromodiphenylmethane 

Downstream Products

• 89028-36-4 Boc-Cys(Dpm)-Ala-OMe 
• 113787-87-4 N-(t-butyloxycarbonyl)-S-(diphenylmethyl)-L-cysteinyl-D-valine benzhydryl ester 
• 123347-85-3 C₉₁H₁₁₈N₁₂O₁₈S 
• 10389-65-8 di-t-butoxycarbonyl-L-cystine 
• 113787-88-5 S-(diphenylmethyl)-L-cysteinyl-D-valine benzhydryl ester 
• 113787-89-6 iodoacetyl-L-(S-diphenylmethyl)cysteinyl-D-valine benzhydryl ester 
• 113787-91-0 2-<3-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine 
• 113787-90-9 2-<3-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine benzhydryl ester 
• 89028-35-3 N-tert.-Butyloxycarbonyl-S-trityl-L-cysteinyl-S-diphenylmethyl-L-cysteinyl-L-alanyl-glycyl-L-valin-hydrazid 
• 89028-34-2 N-tert.-Butyloxycarbonyl-S-trityl-L-cysteinyl-S-diphenylmethyl-L-cysteinyl-L-alanyl-glycyl-L-valin-methylester 
• 89028-33-1 N-tert.-Butyloxycarbonyl-S-trityl-L-cysteinyl-S-diphenylmethyl-L-cysteinyl-L-alanin-hydrazid 
• 89028-32-0 N-tert.-Butyloxycarbonyl-S-trityl-L-cysteinyl-S-diphenylmethyl-L-cysteinyl-L-alanin-methylester 

Relevant academic research and scientific papers

Synthesis of a Protected Cyclic Disulphide Octapeptide A6-13 of the (Ala12)-Sheep Insulin-A-Chain

The synthesis of a protected (Ala12)-sheep insulin-A-chain octapeptide with a 6,11-disulphide ring using the combination of A6,11-S-trityl/A7-S-diphenylmethyl thiol protecting groups is described.For the formation of the cyclic disulphide octapeptide 2 the linear octapeptide, Boc-Cys(Trt)Cys(Dpm)AlaGlyValCys(Trt)Ala-Leu-OH (1), is prepared by a 4 + 4- as well as a 3 + 2 + 3-fragment condensation scheme followed by treatment with iodine in methanol.Most of the peptide coupling reactions were performed using the azide technique obtaining the intermediate peptide fragments in good yields.For the characterization of the cyclic disulphide peptide 2 the 13C-n.m.r.-spectroscopy was used in combination with other usual methods.