219475-92-0Relevant academic research and scientific papers
Orthoester-condensation/C-O insertion reaction sequence for the preparation of tetrahydrofurans
Calter, Michael A.,Sugathapala, Priyantha M.
, p. 8813 - 8816 (2007/10/03)
This paper describes a general procedure for the efficient preparation of highly substituted tetrahydrofurans. The condensation of α-diazo-β- ketoester-derived enolates with orthoesters yields diazoacetals 1a-1d. These compounds undergo formal C-O inserti
