219497-33-3

Upstream product

• 141215-69-2 methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(1H-indol-3-yl)propanoate 
• 4299-70-1 L-tryptophan methyl ester 
• 73-22-3 L-Tryptophan 
• 100-39-0 benzyl bromide 

Downstream Products

• 181363-91-7 N¹-benzyl-N¹⁰-[5,6-dicarbomethoxy-3-(1,2,4-triazinyl)]-(L)-tryptophan methyl ester 
• 110659-38-6 N-t-butoxycarbonyl-tryptophanol 
• 129784-64-1 N¹-benzyl-(L)-tryptophan methyl ester 

Relevant academic research and scientific papers

New small molecule inhibitors of hepatitis C virus

New small molecule inhibitors of HCV were discovered by screening a small library of indoline alkaloid-type compounds. An automated assay format was employed which allowed identification of dimerization inhibitors of core, the capsid protein of the virus. These compounds were subsequently shown to block production of infectious virus in hepatoma cells.

Intramolecular inverse electron demand Diels-Alder reactions of tryptamine with tethered heteroaromatic azadienes

1,2,4,5-Tetrazines and 1,2,4-triazines tethered to tryptamine via the ethylamine side chain undergo intramolecular inverse electron demand cycloadditions to produce adducts with the [ABazaCE]-ring skeleton of the Aspidosperma alkaloids. (C) 2000 Elsevier Science Ltd.