219509-82-7

Usage

Uses

Used in Pharmaceutical Industry:
1-BOC-4-ETHOXYCARBONYL PIPERAZINE is used as a building block for the preparation of various pharmaceuticals, contributing to the development of new drug candidates due to its versatile chemical structure and pharmacological properties.
Used in Agrochemical Industry:
1-BOC-4-ETHOXYCARBONYL PIPERAZINE is used as a building block for the synthesis of agrochemicals, playing a role in the development of new compounds for agricultural applications.
Used in Organic Synthesis:
1-BOC-4-ETHOXYCARBONYL PIPERAZINE is used as a reagent in organic synthesis, facilitating the preparation of a wide range of fine chemicals and biologically active molecules.
Used in Medicinal Chemistry and Drug Discovery:
1-BOC-4-ETHOXYCARBONYL PIPERAZINE is used as a starting material in medicinal chemistry and drug discovery, leveraging its pharmacological properties to develop innovative drug candidates for various therapeutic areas.

Upstream product

• 64-17-5 ethanol 
• 530-62-1 1,1'-carbonyldiimidazole 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 541-41-3 chloroformic acid ethyl ester 

Relevant academic research and scientific papers

OXAZOLIDINE-BASED COMPOUND AND SELECTIVE ANDROGEN RECEPTOR AGONIST COMPRISING SAME

Provided are novel selective androgen receptor agonists, a preparation method thereof, and a pharmaceutical composition including the same at a pharmaceutically effective amount. The selective androgen receptor agonists according to the present invention

HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF

Disclosed are heteroaryl derivatives, pharmaceutical composition and uses in the manufacture of a medicine for treating respiratory diseases, especially for chronic obstructive pulmonary disease (COPD).

Aromatic heterocyclic derivatives and applications of aromatic heterocyclic derivatives in medicines

The present invention discloses aromatic heterocyclic derivatives and applications of the aromatic heterocyclic derivatives in medicines, and specifically provides a class of aromatic heterocyclic compounds or stereoisomers, geometric isomers, tautomers, racemic bodies, nitrogen oxides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs thereof, and pharmaceutical compositions containing the compounds. The present invention further discloses uses of the compounds or pharmaceutical compositions in drug preparation, wherein the drug is used for treatment of respiratory diseases, particularly chronic obstructive pulmonary disease (COPD).

Substituted phenoxypropyl-(R)-2-methylpyrrolidine aminomethyl ketones as histamine-3 receptor inverse agonists

Optimization of a series of aminomethyl ketone diamine H3R antagonists to reduce the brain exposure by lowering the pKa, led to molecules with improved pharmacokinetic properties. Compounds 9, 19, and 25 had high affinity for human H3R and demonstrated in vivo H3R functional activity in the rat dipsogenia model. Compound 9 displayed modest wake-promoting activity in the rat EEG/EMG model.

Unsymmetrical tetrasubstituted ureas from tertiary carbamoylimidazole: Activation by AlMe3

An efficient and general method for the synthesis of unsymmetrical tetrasubstituted ureas from carbamoylimidazole is described. The conversion is achieved by the concurrent quarternization of the imidazole nitrogen and activation of amines with AlMe3. The Royal Society of Chemistry 2012.