219536-50-2

Upstream product

• 32934-24-0 ethyl 2,3,4,6-tetra-O-acetyl-1-thio-α-D-glycopyranoside 
• 604-69-3 β-D-glucose pentaacetate 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 7473-36-1 (2R,3R,4S,5S,6R)-2-Ethylsulfanyl-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 

Downstream Products

• 883557-03-7 ethyl 2-O-(4-acetoxy-2,2-dimethylbutanoyl)-4,6-O-benzylidene-1-thio-α-D-glucopyranoside 
• 402831-59-8 ethyl 2-azido-4,6-O-benzylidene-2-deoxy-1-thio-α-D-mannopyranoside 
• 1309361-03-2 ethyl 2-O-benzyl-3,4,6-tri-O-benzoyl-1-thio-α-D-glucopyranoside 
• 1309361-05-4 ethyl 2-O-benzyl-1-thio-α-D-glucopyranoside 
• 1309361-04-3 ethyl 2-O-benzyl-4,6-benzylidene-1-thio-α-D-glucopyranoside 

Relevant academic research and scientific papers

A NOVEL SYNTHETIC NEISSERIA MENINGITIDIS SEROGROUP A OLIGOMER AND PROCESS FOR SYNTHESIZING THEREOF

The present invention relates to novel synthetic Neisseria meningitidis Serogroup A (hereinafter MenA) capsular polysaccharide repeating unit oligomer and a process for synthesizing said synthetic MenA capsular polysaccharide repeating unit oligomer. More specifically, the present invention relates to the chemical synthesis of the tetramer of MenA capsular polysaccharide repeating unit capable of being used as a candidate in the development of semisynthetic or fully synthetic conjugate vaccines as monovalent or as a part of combination vaccines against Meningococcal serogroup A bacterial infection.

Method for synthesis of beta glucans

The invention provides a method for forming P-glucoside linkages in carbohydrate polymers, particularly synthetic glucan molecules, by attaching a protecting group to the C2 position of a glucoside donor. The protecting group of the invention stabilizes t

Regioselective Lipase-catalysed acylation of 4,6-O-benzylidene-α- and - β-D-pyranoside derivatives displaying a range of anomeric substituents

The application of Lipase enzymes to effect regioselective C-3-O- acylation of 4,6-O-benzylidene-β-D-gluco- and -galactopyranosides displaying a range of anomeric substituents, and C-2-O-acylation of phenyl 4,6-O- benzylidene-α-D-glucopyranoside and ethyl 4,6-O-benzylidene-1-thio-α-D- glucopyranoside is reported. In particular this method has allowed introduction of a variety of acyl protecting groups at the C-3 hydroxyl group of ethyl 4,6-O-benzylidene-1-thio-β-D-glucopyranoside 11.